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Aim: The objectives of this study was to study the various micro-organisms causing surgical site infection, to study their antibiotic sensitivity and resistance pattern. Setting: Department of Surgery of a tertiary health care centre with an attached medical college. Material and methods: A total of 89 patients with post operative surgical site infection occurring within 30 days of surgery or 1 year of implant were included as subject material after they satisfy inclusion and exclusion criteria. Results: E.coli is the commonest organism isolated in SSI wounds. Overall Imipenem and Amikacin are the most sensitive antibiotics. Over all gentamycin, cefotaxime and clindamycin are the most resistant antibiotics noted. Conclusion: The most common organisms associated with SSI are E. coli and Pseudomonas. Most of the organisms were sensitive to imipenem, amikacin. Sensitivity pattern of the of the organism is changing with time. The common organisms are now no longer sensitive to routinely used cheaper antibiotics. Newer antibiotics, which are more costly, are required to treat the infection which is a burden to the patient.

Keywords

Antibiotic Resistance Pattern, Antibiotic Sensitivity Pattern, Co-Morbidity.
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