Open Access
Subscription Access
Open Access
Subscription Access
Booroolo Allele Segregation in Garole Maluro and GM Sheep
Subscribe/Renew Journal
Garole Sheep of west Bengal (India) is known to carry mutation in an autosomal gent FecB (Boraola allel or FecB+) on ovine chromosome 6. The mutation is known to affect Ovulation rate and in turn litter size in Garole sheep. The mutated allel is hypothesized to be the original genotype of the breed and by this virtue the sheep produces twins, triplets and quadruplets. To incorporate the character of higher prolificacy in mutation type non-prolific Malpura sheep of semi-arid region of Rajasthan, Garole sheep was used as sire breed in FecB introgression programme started in 1997 at Central sheep and wool Research Institute, Avikanagar. Presence of FecB allel was detected in Garole and GM sheep. The genotype frequencies of homozygous carriers (FecBB+) were 0.41 and 0.11 in Garole and GM, respectively. The corresponding Figures for heterozygous (FecbB+) were 0.48 and 0.60 in Garole and GM, respectively.
Keywords
Fecundity Gene FeeB, Garole, Gene Frequency, Genotypic Frequency, Sheep.
Subscription
Login to verify subscription
User
Font Size
Information
- Bose, S. Dutta, Gupta, R. and Moitra, D.N. (1999). Reproductive performance of Bengal sheep in Sunderbans. Indian J. Anim. Prod. & Mgmt., 15:157-160.
- Davis, G.H., Balakrishna, L., Ross, I. K., Wilson, T., Galloway, S. M., Lumsedn, B. M., Hanrahan, J. P., Mullen, M., Mao, X. Z., Wang, G.L., Zhao, Z.S., Zeng, Y.Q., Robinson, Mavrogenis A. P., Papachristoforou, C., Peter, C., Baumung, R., Cardyn, P., Boujenane, I., Cockett, N. E., Eythorsdottir, E., Arranz, J. and Notter, D.R. (2006). Inverstigation of the Booroola (FecB) and Inverdale (FecX1) mutations in 21 prolific breeds and strains of sheep sampled in 13 countries.Anim. Repr. Sci.,92(1&2):87-96.
- Davis, G.H., Galloway, S.M., Ross, I.K., Gregan, S.M., Ward, J., Nimbkar, B.V., Ghalsasi, P.M., Nimbkar, C., Gray, G.D., Subandriyo, Inounu I., Tiesnamurti, B., Martyniuk, E., Eythorsdottir, E., Mulsant, P., Lecerf, F., Hanrahan, J.P., Bradford, G.E. and Wilson, T. (2002). DNA tests in prolific sheep from eight countries provide new evidence on origin of the Booroola (FecB) mutation. Biol. Repr., 66 (6) : 1869-1874.
- Davis, G. H., Montgomery, G.W., Allison, A. J., Kelly, R.W. and Bray, A.R. (1982). Segregation of major gene influencing fecundity in progeny of Booroola sheep. New Zealand J. Agric. Res., 25 : 525-529.
- Elsen, J.M., Boding, L. and Thomomer, J. (1990). Major genes for reproduction in sheep. Second Inteternational Booroola Workshop Toulous, France, July 16-18.
- Fabre, S., Pierre, A. Pisselet, C, Mulsant, P. Lecelef, P., Pohi, J., Monget, P. and Monniaux, D. (2003). The Booroola mutation in sheep is associated with an alteration of the bone morphogenetic protein receptor IB Functionality. J. Endocriomol., 177 : 435-444.
- Kleeman, D.O., Ponzoni, R.W., Stafford, J. E. and Grimson, R. J. (1985). Growth and carcass characters of south Australian Merion and its crosses with the Booroola and Trangie fertility Merino. Australian J. Exp. Agric., 25 : 750-757.
- Montromery, G. W., McNatty, K. and Davis, G.H. (1992). Physiology and molecular genetics of mutations that increase ovulation rate in sheep. Endocrine Rev., 13 : 309-320.
- Mulsant, P., Lecerf, F., Fadre, S., Schibles, I., Monget, P., Lamelac, I., Pisslet, C., Riquet, J., Monniaux, D., Cattebout, I., Crobin, E., Thimonier, J., Teyssier, J., Bodin, I., Cognie, V., Chitour, N. and Elsea, J.M. (2001). Mutation in bone morphogenetic protein receptor IB is associated with increased ovulation rate in Booroola merino ewes. Proceeding National Academy of Science USA 98 5104-09.
- Piper, L. R. and Bindon, B. M. (1982). The Booroola Merino and the Performance of medium non-Peppin crosses at Armidale (Eds) piper I. R, Bindon B M and Nethery R D the Booroola Merino Commonwealth scientific and Industrial Research Organization Melbourne pp.9.
- Sharma, R.C., Arora, A.L. and Khan, B.U. (2001). Garole A Prolific sheep of India Central Sheep and wool research Institute Avikanagar (RAJASTHAN) INDIA.
- Visscher, A.H., Drjkstra, M., Lord, E.A,. Suss, R., Rosler, H.J., Heylen, K. and Veerkamp, R.F. (2000). Maternal and lamb carrier effects of the Booroola gene on food intake growth and carcass quality of male lambs. Anim. Sci., 71 : 209-217.
- Willingham, T.D., Waldron, D.W. and Thompson, P.V. (2002). Effect of FecB allele on birth weight and post weaning production traits of Rambouillet Booroola cross wethers Sheep and Goat Wool and Mohair Research Reports, 2002 1-6.
- Wilson, T., Wu, X.Y., Juengel, J.L., Ross, I.K., Lumsden, J.M., Lord, E.A., Dodds, K.G., Walling, G. A., MeEwan, J.C.O., Connell, A.R., McNatty, K.P. and Montgomery, G.W. (2001). Highly prolific Booroola sheep have a mutation in the intracellular kinase domain of bone morphogenetic protein IB receptor (ALK-6) that is expressed in both oocytes and granulose cells Biol. Reprod., 64 : 1225 - 1235.
Abstract Views: 430
PDF Views: 1