Synthesis, Characterization and Hemocompatibility Evaluation of Polyurethane Ionomers

The polyurethane ionomers were synthesized at two temperature range using PEG, different diisocyanate [Tolylene diisocyanate (TDI), 1,6-diisocyanatohexane (HMDI), Isophorone diisocyanate (IPDI), 4,4'- methyl bis(cyclohexyl isocyanates) (H₁₂MDI), 4,4'- methyl bis(phenyl isocyanates) (MDI)] and dihydroxy benzoic acid. All the polymer solutions were cast in a mold to form a film on evaporation of the solvent. All the films were conditioned and characterized by FT-IR, FT-NMR, Gel permeation chromatography and particle size analysis. The hemocompatibility of the polyurethane films were determined by thrombogenicity, haemolysis and platelet adhesion test. The PUs synthesized from TDI and HMDI showed better hemocompatibility at higher temperature range (90-95 °C) than the other polymers.