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Analysis of Lymphoma Neoplasm and their Phenotypes


Affiliations
1 Department of Chemical Engineering, SSN College of Engineering, Kalavakkam – 603 110, India
     

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The aim of this project was to determine the significance of lactate dehydrogenase (LDH), β2 microglobulin (β2M) and tumor markers in the diagnosis of lymphoma. For this purpose, 10 patients were taken for study, Median age 55 (35-75), male 7. Histopathologic diagnosis was B-cell lymphoma in 4 (50%), T-cell Lymphoma in 3 (37.5%). 2 patients (20%) were diagnosed with Hodgkin's Lymphoma. Diseases sites were para-aortic nodes (52%), cervical (8%), peripheral nodes (33%), others 6%. The patients were tested for LDH and β2 microglobulin levels in addition to tumor marker analysis.LDH and β2 microglobulin are prognostic indicators. They are also helpful in monitoring the disease during therapy by ascertaining the tumor burden.

Keywords

Lymphoma, Lactate Dehydrogenase,Microglobulin, Tumor markers.
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  • Analysis of Lymphoma Neoplasm and their Phenotypes

Abstract Views: 218  |  PDF Views: 0

Authors

P. Shekar
Department of Chemical Engineering, SSN College of Engineering, Kalavakkam – 603 110, India
G. Krithega Devi
Department of Chemical Engineering, SSN College of Engineering, Kalavakkam – 603 110, India
K. Sathish Kumar
Department of Chemical Engineering, SSN College of Engineering, Kalavakkam – 603 110, India

Abstract


The aim of this project was to determine the significance of lactate dehydrogenase (LDH), β2 microglobulin (β2M) and tumor markers in the diagnosis of lymphoma. For this purpose, 10 patients were taken for study, Median age 55 (35-75), male 7. Histopathologic diagnosis was B-cell lymphoma in 4 (50%), T-cell Lymphoma in 3 (37.5%). 2 patients (20%) were diagnosed with Hodgkin's Lymphoma. Diseases sites were para-aortic nodes (52%), cervical (8%), peripheral nodes (33%), others 6%. The patients were tested for LDH and β2 microglobulin levels in addition to tumor marker analysis.LDH and β2 microglobulin are prognostic indicators. They are also helpful in monitoring the disease during therapy by ascertaining the tumor burden.

Keywords


Lymphoma, Lactate Dehydrogenase,Microglobulin, Tumor markers.