Research Journal of Pharmaceutical Dosage Form and Technology

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Pharmaceutical Excipients- Their Mechanisms


Affiliations
1 Department of Pharmaceutics, Sree Dattha Institute of Pharmacy, Sheriguda, Ibrahimpatnam. Ranga Reddy, District Andhra Pradesh -506501, India
2 Department of Pharmaceutics, Sree Dattha College of Pharmacy, R.R., Dt., A.P, India
3 Department of Pharmaceutics, St. Pauls College of Pharmacy, R.R., Dt., A.P, India
4 Department of Pharmaceutics, Sree Dattha College of Pharmacy, R.R., Dt., Andhra Pradesh, India
     

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Additives are non drug component for structuring dosage form and said to be pharmacologically inactive in nature. Selections of excipients were depend upon type of dosage form, their functionality and based on their compatible atmosphere with respect to the active and inactive ingredients and method of preparation. Their role is vital and forming back bone of type of dosage form including solid, semi-solid and liquid dosage form used for topical and conventional application. To turn a drug (API) substance into a desired pharmaceutical dosage form or a drug delivery system, pharmaceutical ingredients were required. Majority of times formulation stability and their bioavailability depends upon selection of excipients and their concentration level with combinations. The peer knowledge of current review article enlists the different mechanisms of various additives used in multi formulations with their ultimate mechanism role in-depth basics and their background knowledge in designing of various dosage formulations.
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  • Pharmaceutical Excipients- Their Mechanisms

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Authors

K. Venkata Ramana Reddy
Department of Pharmaceutics, Sree Dattha Institute of Pharmacy, Sheriguda, Ibrahimpatnam. Ranga Reddy, District Andhra Pradesh -506501, India
K. Divakar
Department of Pharmaceutics, Sree Dattha College of Pharmacy, R.R., Dt., A.P, India
B. Venkateswara Reddy
Department of Pharmaceutics, St. Pauls College of Pharmacy, R.R., Dt., A.P, India
P. Shruti
Department of Pharmaceutics, Sree Dattha College of Pharmacy, R.R., Dt., Andhra Pradesh, India

Abstract


Additives are non drug component for structuring dosage form and said to be pharmacologically inactive in nature. Selections of excipients were depend upon type of dosage form, their functionality and based on their compatible atmosphere with respect to the active and inactive ingredients and method of preparation. Their role is vital and forming back bone of type of dosage form including solid, semi-solid and liquid dosage form used for topical and conventional application. To turn a drug (API) substance into a desired pharmaceutical dosage form or a drug delivery system, pharmaceutical ingredients were required. Majority of times formulation stability and their bioavailability depends upon selection of excipients and their concentration level with combinations. The peer knowledge of current review article enlists the different mechanisms of various additives used in multi formulations with their ultimate mechanism role in-depth basics and their background knowledge in designing of various dosage formulations.