Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Floating Drug Delivery System:An Innovative Acceptable Approach in Gastroretentive Drug Delivery


Affiliations
1 Maratha Mandal’s College of Pharmacy, Belgaum-590016, Karanataka, India
2 A.P.M.C. College of Pharmaceutical Education and Research, Motipura, Himatnagar-383001, Gujarat, India
     

   Subscribe/Renew Journal


Controlled release (CR) dosage forms have been extensively used to improve therapy with several important drugs. The recent developments of floating drug delivery systems (FDDS) including the physiological and formulation variables affecting gastric retention, approaches to design single-unit and multiple-unit floating systems, and their classification and formulation aspects are covered in detail. This review also summarizes the in vitro techniques, in vivo studies to evaluate the performance and application of floating systems. Floating dosage form can be prepared as tablets, capsules by adding suitable ingredients as well as by adding gas generating agent. In this review various techniques used in floating dosage forms along with current and recent developments of stomach specific floating drug delivery system for gastro retention are discussed.

Keywords

Floating Drug Delivery Systems, Mechanism, Single Unit, Multiple Units, Evaluation Method.
Subscription Login to verify subscription
User
Notifications
Font Size


Abstract Views: 270

PDF Views: 0




  • Floating Drug Delivery System:An Innovative Acceptable Approach in Gastroretentive Drug Delivery

Abstract Views: 270  |  PDF Views: 0

Authors

Nirav Patel
Maratha Mandal’s College of Pharmacy, Belgaum-590016, Karanataka, India
C. Nagesh
Maratha Mandal’s College of Pharmacy, Belgaum-590016, Karanataka, India
S. Chandrashekhar
Maratha Mandal’s College of Pharmacy, Belgaum-590016, Karanataka, India
Patel Jinal
A.P.M.C. College of Pharmaceutical Education and Research, Motipura, Himatnagar-383001, Gujarat, India
Jani Devdatt
Maratha Mandal’s College of Pharmacy, Belgaum-590016, Karanataka, India

Abstract


Controlled release (CR) dosage forms have been extensively used to improve therapy with several important drugs. The recent developments of floating drug delivery systems (FDDS) including the physiological and formulation variables affecting gastric retention, approaches to design single-unit and multiple-unit floating systems, and their classification and formulation aspects are covered in detail. This review also summarizes the in vitro techniques, in vivo studies to evaluate the performance and application of floating systems. Floating dosage form can be prepared as tablets, capsules by adding suitable ingredients as well as by adding gas generating agent. In this review various techniques used in floating dosage forms along with current and recent developments of stomach specific floating drug delivery system for gastro retention are discussed.

Keywords


Floating Drug Delivery Systems, Mechanism, Single Unit, Multiple Units, Evaluation Method.