Liquisolid Technique for Solubility Enhancement of Poorly Water Soluble Drugs

This review covers the detail aspects of Liquisolid formulation technique for solubility enhancement of poorly water soluble drugs. Over the years various methods are developed to enhance the drug solubility, liquisolid technique is one of promising the technique. The new fundamental mathematical model introduced by S. Spires and M. Bolton, 1999, helps to formulate the liquisolid systems. Formulation and development by liquisolid systems provides unprecedented opportunities for poorly water soluble drugs.