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Mucoadhesion Based Solid Dosage Form: The Next Generation


Affiliations
1 B.I.S. College of Pharmacy, Gagra, Moga-142103, Punjab, India
2 C.T. College of Pharmacy, Jalandhar-144001, Punjab, India
3 Department of Pharmaceutical sciences, University of Kashmir, Srinagar-190001, J&K, India
4 Akal College of Pharmacy, Mastuana Sahib, Sangrur-148001, Punjab, India
     

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This review reveals the potential of mucoadhesive polymers and tablets for gastrointestinal administration. Prolonged contact time of a drug with a body tissue through the use of mucoadhesive polymers can significantly improve the performance of many drugs. These improvements lead to better treatment of local pathologies, improved drug bioavailability and control release of the drug to enhanced patient compliance. This review highlights the role of next generation mucoadhesive polymers and the benefits likely to occur with these improved polymeric systems. New mucoadhesive materials with optimal adhesive properties are now being developing and explored to enhance the application of this technology.

Keywords

Mucoadhesive, Polymers, Gastroretention, Bioavailability.
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  • Mucoadhesion Based Solid Dosage Form: The Next Generation

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Authors

Navneet Nagpal
B.I.S. College of Pharmacy, Gagra, Moga-142103, Punjab, India
Arora Manisha
B.I.S. College of Pharmacy, Gagra, Moga-142103, Punjab, India
Rahar Sandeep
B.I.S. College of Pharmacy, Gagra, Moga-142103, Punjab, India
Swami Gaurav
C.T. College of Pharmacy, Jalandhar-144001, Punjab, India
Sharma Dinesh
Department of Pharmaceutical sciences, University of Kashmir, Srinagar-190001, J&K, India
Kapoor Reni
Akal College of Pharmacy, Mastuana Sahib, Sangrur-148001, Punjab, India

Abstract


This review reveals the potential of mucoadhesive polymers and tablets for gastrointestinal administration. Prolonged contact time of a drug with a body tissue through the use of mucoadhesive polymers can significantly improve the performance of many drugs. These improvements lead to better treatment of local pathologies, improved drug bioavailability and control release of the drug to enhanced patient compliance. This review highlights the role of next generation mucoadhesive polymers and the benefits likely to occur with these improved polymeric systems. New mucoadhesive materials with optimal adhesive properties are now being developing and explored to enhance the application of this technology.

Keywords


Mucoadhesive, Polymers, Gastroretention, Bioavailability.