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Anti-Inflammatory Activity of Ethanolic and Acetone Extracts of Bauhnia variegate
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The ethanolic and acetone extracts of Bauhnia variegate bark was examined for anti-inflammatory in experimental animals. In this study both acute and sub-acute inflammation models were used to evaluate the antiinflammatory activity of the Bauhnia variegate. In acute model carrageenan was used to induce inflammation in rat hind paw and in sub-acute inflammation, cotton pellet induced granuloma was performed. The bark of ethanolic and acetone extracts of bauhnia variegate at the doses of 400 mg/kg shows significant (p<0.001) inhibition of inflammation against both acute and sub-acute anti-inflammatory model. The percentage inhibition of ethanolic and acetone extract of Bauhnia variegate both acute and subacute anti-inflammatory model was 35.29%, 43.14% and 33.53%, 42.20% respectively. According to our results both the extracts of Bauhnia variegate in doses of 400 mg/kg reveals anti-inflammatory activity and supports tribal claim.
Keywords
Anti-Inflammatory, Carrageenan, Cotton Pellet Granuloma and Bauhnia Variegate.
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