Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Anti-Inflammatory Activity of Ethanolic and Acetone Extracts of Bauhnia variegate


Affiliations
1 Department of Pharmacology, Sri K .V College of Pharmacy, M.G.Road, Chickballapur-562101, Karnataka., India
2 Department of Pharmacology, Sri K .V College of Pharmacy, M.G.Road, Chickballapur-562101, India
     

   Subscribe/Renew Journal


The ethanolic and acetone extracts of Bauhnia variegate bark was examined for anti-inflammatory in experimental animals. In this study both acute and sub-acute inflammation models were used to evaluate the antiinflammatory activity of the Bauhnia variegate. In acute model carrageenan was used to induce inflammation in rat hind paw and in sub-acute inflammation, cotton pellet induced granuloma was performed. The bark of ethanolic and acetone extracts of bauhnia variegate at the doses of 400 mg/kg shows significant (p<0.001) inhibition of inflammation against both acute and sub-acute anti-inflammatory model. The percentage inhibition of ethanolic and acetone extract of Bauhnia variegate both acute and subacute anti-inflammatory model was 35.29%, 43.14% and 33.53%, 42.20% respectively. According to our results both the extracts of Bauhnia variegate in doses of 400 mg/kg reveals anti-inflammatory activity and supports tribal claim.

Keywords

Anti-Inflammatory, Carrageenan, Cotton Pellet Granuloma and Bauhnia Variegate.
Subscription Login to verify subscription
User
Notifications
Font Size


Abstract Views: 242

PDF Views: 0




  • Anti-Inflammatory Activity of Ethanolic and Acetone Extracts of Bauhnia variegate

Abstract Views: 242  |  PDF Views: 0

Authors

D. Sheshadri Shekar
Department of Pharmacology, Sri K .V College of Pharmacy, M.G.Road, Chickballapur-562101, Karnataka., India
C. Velmurugan
Department of Pharmacology, Sri K .V College of Pharmacy, M.G.Road, Chickballapur-562101, India
G. Ramakrishnan
Department of Pharmacology, Sri K .V College of Pharmacy, M.G.Road, Chickballapur-562101, India
B. Vivek
Department of Pharmacology, Sri K .V College of Pharmacy, M.G.Road, Chickballapur-562101, India

Abstract


The ethanolic and acetone extracts of Bauhnia variegate bark was examined for anti-inflammatory in experimental animals. In this study both acute and sub-acute inflammation models were used to evaluate the antiinflammatory activity of the Bauhnia variegate. In acute model carrageenan was used to induce inflammation in rat hind paw and in sub-acute inflammation, cotton pellet induced granuloma was performed. The bark of ethanolic and acetone extracts of bauhnia variegate at the doses of 400 mg/kg shows significant (p<0.001) inhibition of inflammation against both acute and sub-acute anti-inflammatory model. The percentage inhibition of ethanolic and acetone extract of Bauhnia variegate both acute and subacute anti-inflammatory model was 35.29%, 43.14% and 33.53%, 42.20% respectively. According to our results both the extracts of Bauhnia variegate in doses of 400 mg/kg reveals anti-inflammatory activity and supports tribal claim.

Keywords


Anti-Inflammatory, Carrageenan, Cotton Pellet Granuloma and Bauhnia Variegate.