Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

An Overview of Pharmaceutical Mini Tablet


Affiliations
1 Department of Pharmaceutics, Ali-Allana College of Pharmacy Akkalkuwa, Dist.: Nandurbar (425415), Maharashtra,, India
     

   Subscribe/Renew Journal


The objective of controlled drug delivery systems is to decrease the frequency of dosing and to increase the efficiency of the drug by localization. In oral controlled drug delivery systems, Mini-tablets represent the new trend in Solid oral dosage forms are most acceptable dosage forms especially tablets are most widely accepted by people of different age groups. Mini tablets with a diameter alike to or smaller than 3–6 mm. mini tablets are multiple unit dosage forms and are convenient to pellets or any other oral dosage forms as there calm to manufacture and stability snags are less. Some types of mini tablets are like to Oral disintegrating mini tablets, pH responsive mini tablets, Biphasic mini tablets, gastro retentive mini tablets, paediatric mini tablets, and bio adhesive mini tablets.

Keywords

Mini Tablet, MUDFs, SUDFs, Compressed mini tablet, Pellets.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Priyanka. Kapil K. Deepak T et al A comprehensive review on pharmaceutical mini tablets, Journal of Drug Delivery and Therapeutics. 2018; 4(6): 382-390
  • Thanoo BC. Sunny M.C. Jaya krishnan A et al Oral Sustained release Drug delivery systems using polycarbonate microspheres capable of floating on the gastric fluid, J Pharm. and Pharmacol 1993; 45: 21-24
  • Aulton, ME. Eds Pharmaceutics: The Science of Dosage Form Design, Churchill Livingstone, Edinburgh, pp 2005; 290-294: 398- 416
  • Christopher T. Rhodes. Gilbert S. Banker et al Modern Pharmaceutics Fourt Edition, 2012; pp291: 503- 504
  • Mehta R.M. pharmaceutics; Vallabh Prakashan 2002; 1:3: pp 238.
  • Costa P. Lopes CM. Sousa Lobo JM et al A Compressed Mini tablets as a biphasic drug delivery system, International journal of Pharmaceutics, 2006; 323(1–2): 93–100
  • Karthikeyan D. Vijayalaxmi A. Santhosh Kumar C et al Formulation and evaluation of biphasic Delivery --system of Aceclofenac mini tablets in Hard gelatin capsules, Int j of novel trends in pharmaceutical sciences, ISSN: 2277–2782, 2013; 3(2) 39-45
  • Rutvik Patel. Punit Parejiya. Bhavik Solanki. Pragna Shelat et al A Multiple Unit Dosage Forms: Review on, Pharmtechmedica, 2013; 1(1): 11-21
  • Mielck J. Lennartz P. Mini-tabletting have improving the compactability of paracetamol powder mixtures. Int Journal of Pharm. 1998; 173: P.75 – 85
  • Ghosh B. Reddy L.H, Rajneesh. et al Fast-dissolving drug delivery systems: a review on the literature, Indian Journal of Pharmaceutical Sciences, 2002; 64(4): 331- 336
  • Mielck JB, Flemming J. A Requirements for the making of microtablets - suitability by direct-compression excipients and appraised from powder appearances and flow-rates. Drug Dev Ind J Pharm, 1995; 21: 2239–2251
  • Bhavik S. Rutvik Patel. Bhavesh Barot. Pragna Shelat et al Multiple Unit of Dosage Forms: A Review on, Pharmtechmedica 2012; 1(1): 11-21
  • Breitkreutz J. Tissen C. Woertz K, Kleinebudde P. et al Development of a Mini tablets with 1 mm or 2 mm diameter. International Journal of Pharm. 2011; 416: 164-170
  • Kranz H, Riis T, Bauer-Brandl A., An pH-independent drug release of an enormously poorly soluble and feebly acidic drug from multi-particulate lengthy-release formulations. European Journal of Biopharm.2007; 65: 78-84
  • Ghebre-Selassie I. A Multi particulate oral drug delivery system, Marcel Dekker, Drugs and the Pharmaceutical Sciences. Taylor and Francis, New York, 2008; 65: 307-312
  • Raghavendra Rao N.G, Mohd Abdul Hadi, et al A Novel Techniques in a Formulations. An Overview, World Journal of Pharmaceutical Research, 2012; 1(3): 1-17
  • Pogula AH, Nazeer S.et al “Extended-Release Formulation” International Journal of Pharmacy and Technology.2010
  • Sannapu A. Rao V.U.M. Keerthi ML. Kiran R.S, Dutt A.G et al An Pharmaceutical Mini-Tablets, and its Advantages, Formulation or Possibilities and Common Evaluation Aspects: A Review. International J. of Pharm. Sci. Rev. Res. 2014; 28: 214-221.
  • Akarte1 A.M. Mahajan KV. Baviskar D.T, Jain D.K, et al Designing and evaluation of compressed mini-tablets of ramipril as an biphasic drug delivery system. Indo American J of Pharm Research. 2013; 3: 7277-2787
  • Pinto JF. Costa P. Lopes CM. Lobo JM et al As a Directly compressed mini matrix tablets containing ibuprofen: preparation and evaluation of sustained release. Drug. Dev. Ind. Pharm. 2006; 32: 95-106.
  • Bankar V.H. Modi SA, Gaikwad PD, Pawar SP et al “Sustained release drug delivery system: a review” International Journal of Pharma Research and Development, 2011: 1; 47-198. 10
  • Dnyaneshwar S, Vikram N. Sanchati, Saddam C.S, Pooja P Kochar et al Formulation and evaluation of Ibuprofen gastroretentive floating tablets. Universal Journal of Pharm Res., 2018; 3(4): 20-25.
  • James Swarbick, Encyclopedia of Pharmaceutical Technology., 1993; 3: 2652-2663
  • Joao F, Jose Manuel, Carla M, Lopes A, Sousa Loboa, Paulo Costa et al A Compressed mini-tablets as a biphasic drug delivery system, International Journal of Pharmaceutics. 2006; 323: 93– 100.
  • Saleem IY, Tawfeek HM, Matthew Roberts et al dissolution enhancement and formulation of rapid-release lornoxicam minitablets, drug delivery and pharmaceutical technology, 2014; 2470- 2483.
  • Drug dosage forms 11 (PHR 312) Lecture five., tablet coating, tower university in Alexandria (PUA),2013 www.pua.edu.eg/’
  • Nagai T, Hoshi N, Application of HPMC and HPMCAS liquid film coating of pharmaceutical dosage kind. Marcel dramatist, New York, 1989; 81-152
  • Mahlawat G, Singh S, Virmani T, Virmani R, Kumar P. et al a fast dissolving drug delivery systems ‘formulation, preparation techniques and evaluation. Universal Journal of Pharm Res. 2018; 3(4): 60-69.
  • Wan LSC, Heng PWS, Tan YTF et al Mixed powder for changed releas dose kind coated round shape. Pharm Dev Technol. 1999; 4; 561-57
  • Oduola AR. Igwe J. Chibueze, Emenike IV et al Formulation and analysis of Finasteride sustained-release matrix tablets exploitation completely different rate controlling polymers. Univ J Pharm Res. 2016; 1(2): 25-31.
  • Dipak VB. Husain CS. Dnyaneshwar S, Jain S. Pooja P Kochar et al Formulation and analysis of isobutylphenyl propionic acid gastro-retentive floating tablets. Unit J Pharm Res. 2018; 3(4): 20- 25
  • Ying huan, Jia bi Zhu, Modulation of combined unleash behaviors from pill tablet in capsule system’s management unharness. 2004; 95; 381-389
  • Harsh Panchal, Raghavendra Rao NG, Mohd Abdul Hadi et al A Novel approach to sustained Montelukast sodium release: Differentially coated mini-tablets in HPMC capsules, International Journal of Pharmaceutical and Biomedical Sciences; 2011; 2(2): 90-97
  • Vijayalaxmi A, Karthikeyan D, Santhosh Kumar C, et al. Formulation and evaluation of biphasic Delivery system of Aceclofenac mini-tablets in Hard gelatin capsules, International journal of novel trends in pharmaceutical sciences, 2013; 3(2): 39- 45
  • Kiran R.S, Keerthi ML, Rao VUM, Sannapu A, Dutt A.G. et al Pharmaceutical Mini-Tablets, its Advantages, Formulation Possibilities and General Evaluation Aspects: A Review. Int. J. Pharm. Sci. Rev. Res. 2014; 28: 214-221.

Abstract Views: 134

PDF Views: 0




  • An Overview of Pharmaceutical Mini Tablet

Abstract Views: 134  |  PDF Views: 0

Authors

Mohd Salman
Department of Pharmaceutics, Ali-Allana College of Pharmacy Akkalkuwa, Dist.: Nandurbar (425415), Maharashtra,, India
Qazi Majaz A
Department of Pharmaceutics, Ali-Allana College of Pharmacy Akkalkuwa, Dist.: Nandurbar (425415), Maharashtra,, India
Abrarul Haq
Department of Pharmaceutics, Ali-Allana College of Pharmacy Akkalkuwa, Dist.: Nandurbar (425415), Maharashtra,, India
Sandip Raut
Department of Pharmaceutics, Ali-Allana College of Pharmacy Akkalkuwa, Dist.: Nandurbar (425415), Maharashtra,, India

Abstract


The objective of controlled drug delivery systems is to decrease the frequency of dosing and to increase the efficiency of the drug by localization. In oral controlled drug delivery systems, Mini-tablets represent the new trend in Solid oral dosage forms are most acceptable dosage forms especially tablets are most widely accepted by people of different age groups. Mini tablets with a diameter alike to or smaller than 3–6 mm. mini tablets are multiple unit dosage forms and are convenient to pellets or any other oral dosage forms as there calm to manufacture and stability snags are less. Some types of mini tablets are like to Oral disintegrating mini tablets, pH responsive mini tablets, Biphasic mini tablets, gastro retentive mini tablets, paediatric mini tablets, and bio adhesive mini tablets.

Keywords


Mini Tablet, MUDFs, SUDFs, Compressed mini tablet, Pellets.

References