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Characterization of Annona muricata Stem Methanol Extract by Gas Chromatography-Mass Spectrometry Analysis


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1 Department of Chemistry, Michael Okpara University of Agriculture, Umudike, Nigeria
     

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Annona muricata extract are extensively used as traditional remedy for a variety of illnesses like cancer, diabetes, hypertension and malaria. Methanol extract of Annona muricata (soursop) stem were analyzed using gas chromatography-mass spectrometry method. The result obtained from the GC-MS analysis of methanol extract of Annona muricata stem led to identification of ten (10) compounds in which 1-(4-hydroxy-6-methyl-2- pyrimidinyl)-2-aziridinone, hexadecanoic acid (palmitic acid) and 9-octadecanoic acid(oleic acid) are the major component reported with significant bioactive impact. The components were identified by comparing their retention indices and mass spectra fragmentation patterns with those stored in the National Institute of Standards and Technology (NIST) library.

Keywords

Chromatogram, Annona muricata, Retention Indices, Mass Spectra.
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  • Characterization of Annona muricata Stem Methanol Extract by Gas Chromatography-Mass Spectrometry Analysis

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Authors

Okoro Ebere Kelechi
Department of Chemistry, Michael Okpara University of Agriculture, Umudike, Nigeria
Amaku Friday James
Department of Chemistry, Michael Okpara University of Agriculture, Umudike, Nigeria
Okoro Innocent Ajah
Department of Chemistry, Michael Okpara University of Agriculture, Umudike, Nigeria

Abstract


Annona muricata extract are extensively used as traditional remedy for a variety of illnesses like cancer, diabetes, hypertension and malaria. Methanol extract of Annona muricata (soursop) stem were analyzed using gas chromatography-mass spectrometry method. The result obtained from the GC-MS analysis of methanol extract of Annona muricata stem led to identification of ten (10) compounds in which 1-(4-hydroxy-6-methyl-2- pyrimidinyl)-2-aziridinone, hexadecanoic acid (palmitic acid) and 9-octadecanoic acid(oleic acid) are the major component reported with significant bioactive impact. The components were identified by comparing their retention indices and mass spectra fragmentation patterns with those stored in the National Institute of Standards and Technology (NIST) library.

Keywords


Chromatogram, Annona muricata, Retention Indices, Mass Spectra.