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Efficacy of Leaves Extract of Acacia nilotica against Pseudomonas aeruginosa with Reference to Disc Diffusion Method


Affiliations
1 Center for Pharmaceutical Sciences, IST, JNTUH, Kukatpally, Hyderabad-500085, AP, India
2 Gland Institute of Pharmaceutical Sciences, Kothapet, Medak, AP, India
     

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In the past few decades, the search for new anti-infection agents has occupied many research groups in the field of ethno pharmacology. The medicinal plants serve as, potential antimicrobial crude drugs as well as a source for natural compounds that act as new anti-infection agents. The use of plants by man came about through observation of their definite effects on animals and man. Increasing number of plants are been screened for their anti-microbial activity day by day. According to World Health Organization (WHO) more than 80% of the world's population relies on traditional medicine for their primary healthcare needs. The medicinal plant used for current study Acacia nilotica is mostly indicated to be abundant and rare. The methanol, chloroform, hexane and petroleum ether extracts of Acacia nilotica was tested for its efficacy against gram-negative bacteria: Pseudomonas aeruginosa, using disc diffusion method. The result demonstrated that the methanol extract is more efficient than the other solvent extracts in suppressing the bacterial growth in the study.

Keywords

Ethno Pharmacology, Anti-Microbial, Acacia nilotica, Pseudomonas aeruginosa, Disc Diffusion Method.
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  • Efficacy of Leaves Extract of Acacia nilotica against Pseudomonas aeruginosa with Reference to Disc Diffusion Method

Abstract Views: 248  |  PDF Views: 0

Authors

K. Shanker
Center for Pharmaceutical Sciences, IST, JNTUH, Kukatpally, Hyderabad-500085, AP, India
G. Krishna Mohan
Center for Pharmaceutical Sciences, IST, JNTUH, Kukatpally, Hyderabad-500085, AP, India
M. Bhagavan Raju
Gland Institute of Pharmaceutical Sciences, Kothapet, Medak, AP, India
L. Divya
Gland Institute of Pharmaceutical Sciences, Kothapet, Medak, AP, India
B. Sanjay
Gland Institute of Pharmaceutical Sciences, Kothapet, Medak, AP, India

Abstract


In the past few decades, the search for new anti-infection agents has occupied many research groups in the field of ethno pharmacology. The medicinal plants serve as, potential antimicrobial crude drugs as well as a source for natural compounds that act as new anti-infection agents. The use of plants by man came about through observation of their definite effects on animals and man. Increasing number of plants are been screened for their anti-microbial activity day by day. According to World Health Organization (WHO) more than 80% of the world's population relies on traditional medicine for their primary healthcare needs. The medicinal plant used for current study Acacia nilotica is mostly indicated to be abundant and rare. The methanol, chloroform, hexane and petroleum ether extracts of Acacia nilotica was tested for its efficacy against gram-negative bacteria: Pseudomonas aeruginosa, using disc diffusion method. The result demonstrated that the methanol extract is more efficient than the other solvent extracts in suppressing the bacterial growth in the study.

Keywords


Ethno Pharmacology, Anti-Microbial, Acacia nilotica, Pseudomonas aeruginosa, Disc Diffusion Method.