In vitro Anti-Inflammatory Activity of Drynaria quercifolia Rhizome

In the present study, the methanolic extract of Drynaria quercifolia rhizome was investigated for its anti inflammatory activity by Human Red Blood Cell (HRBC) Membrane stabilization method. Different concentration (100, 200 and 300 mcg) of rhizome extract were used and the potency of extract was compared with standard Diclofenac (100, 200 and 300 mcg). Plant extract exhibited notable anti-inflammatory activity in a dose dependent manner. The maximum membrane stabilization was found to be 34.94% for plant extract and 41.62% for standard Diclofenac at a dose of 300 mcg. In conclusion, the results thus obtained suggested that rhizome of Drynaria quercifolia possess considerable antiinflammatory activity and therefore further in vivo studies are needed to establish it as a potent anti-inflammatory agent.