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In-Vitro Anthelmintic Activity on Aqueous and Ethanol Extracts of Abies pindrow Bark


Affiliations
1 Department of Pharmacy, Manav Bharti University, Solan, Himachal Pradesh, India
2 Chemistry Research Lab., R.P. Educational Trust Group of Institutions, Bastara, Karnal, Haryana, India
     

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The anthelmintic activity of ethanol and aqueous extract of Abies pindrow was studied against earthworm Eisenia foetida (redworm). The ethanolic and aqueous extract was prepared by hot and cold respectively. Albendazole was used as the standard drug. The anthelmintic activity was carried out to study the effect of plant extract on adult earthworm Eisenia foetida (redworm), and noted down the paralysis time (Vermifuse), and death time (Vermicidal). It was found that both ethanolic and aqueous extract of bark of Abies pindrow found to have significant action against adult earthworm Eisenia foetida (redworm) at the dose of 25 mg/ml or more; which may be due to the presence of glycosides, carbohydrates, tannins and saponins in the extract. Thus it can be concluded that the bark of Abies pindrow can be used as anthelmintic agent.

Keywords

Abies pindrow, Eisenia foetida and Anthelmintic.
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  • In-Vitro Anthelmintic Activity on Aqueous and Ethanol Extracts of Abies pindrow Bark

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Authors

Shashi Pal Bharti
Department of Pharmacy, Manav Bharti University, Solan, Himachal Pradesh, India
Hitesh Kumar
Department of Pharmacy, Manav Bharti University, Solan, Himachal Pradesh, India
Bharat Parashar
Department of Pharmacy, Manav Bharti University, Solan, Himachal Pradesh, India
Sandeep Deswal
Chemistry Research Lab., R.P. Educational Trust Group of Institutions, Bastara, Karnal, Haryana, India
Nitika Chahar
Chemistry Research Lab., R.P. Educational Trust Group of Institutions, Bastara, Karnal, Haryana, India
Manish Devgan
Chemistry Research Lab., R.P. Educational Trust Group of Institutions, Bastara, Karnal, Haryana, India

Abstract


The anthelmintic activity of ethanol and aqueous extract of Abies pindrow was studied against earthworm Eisenia foetida (redworm). The ethanolic and aqueous extract was prepared by hot and cold respectively. Albendazole was used as the standard drug. The anthelmintic activity was carried out to study the effect of plant extract on adult earthworm Eisenia foetida (redworm), and noted down the paralysis time (Vermifuse), and death time (Vermicidal). It was found that both ethanolic and aqueous extract of bark of Abies pindrow found to have significant action against adult earthworm Eisenia foetida (redworm) at the dose of 25 mg/ml or more; which may be due to the presence of glycosides, carbohydrates, tannins and saponins in the extract. Thus it can be concluded that the bark of Abies pindrow can be used as anthelmintic agent.

Keywords


Abies pindrow, Eisenia foetida and Anthelmintic.