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Phytochemical and Antimicrobial Efficacy of Successive Series of Solanum xanthocarpum


Affiliations
1 Suresh Gyan Vihar University, Jaipur, 22, India
2 Mahatma Gandhi Institute of Applied Sciences, JECRC University, Jaipur-22, India
     

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Antimicrobial activity of the extracts of Solanum xanthocarpum against bacteria and fungus was evaluated. Plant extracts of S. xanthocarpum were prepared in distilled water and in organic solvents, petroleum ether, chloroform, benzene, ethyl acetate and ethanol. Disc diffusion method technique was used to assess the antimicrobial activity of various extracts against Shigella flexneri, Staphylococcus aureus, Salmonella typhi, Pseudomonas aeruginosa, Klebsiella pneumonia, Proteus vulgaris, Enterobacter aerogenes, Aspergillus niger , Candida albicans, Trichophyton rubrum. The diameter of zone of inhibition was taken as an indicator of antimicrobial effect. Except aqueous extracts of S. xanthocarpum, extracts prepared in organic solvents showed antimicrobial activity against the test organisms. Methanol extract showed the best activity against all test microorganisms than other solvent extracts. The maximum efficacy of methanol extract A4 (200mg concentration) was against Staphylococcus aureus (I.Z.-23mm) was screened. Thus, S. xanthocarpum could be considered as a potential source of natural antimicrobials.


Keywords

Solanum xanthocarpum, Antimicrobial Activity, Organic Solvents.
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  • Phytochemical and Antimicrobial Efficacy of Successive Series of Solanum xanthocarpum

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Authors

Sudhanshu
Suresh Gyan Vihar University, Jaipur, 22, India
Mittal Sandhya
Suresh Gyan Vihar University, Jaipur, 22, India
Rao Nidhi
Suresh Gyan Vihar University, Jaipur, 22, India
Menghani Ekta
Mahatma Gandhi Institute of Applied Sciences, JECRC University, Jaipur-22, India

Abstract


Antimicrobial activity of the extracts of Solanum xanthocarpum against bacteria and fungus was evaluated. Plant extracts of S. xanthocarpum were prepared in distilled water and in organic solvents, petroleum ether, chloroform, benzene, ethyl acetate and ethanol. Disc diffusion method technique was used to assess the antimicrobial activity of various extracts against Shigella flexneri, Staphylococcus aureus, Salmonella typhi, Pseudomonas aeruginosa, Klebsiella pneumonia, Proteus vulgaris, Enterobacter aerogenes, Aspergillus niger , Candida albicans, Trichophyton rubrum. The diameter of zone of inhibition was taken as an indicator of antimicrobial effect. Except aqueous extracts of S. xanthocarpum, extracts prepared in organic solvents showed antimicrobial activity against the test organisms. Methanol extract showed the best activity against all test microorganisms than other solvent extracts. The maximum efficacy of methanol extract A4 (200mg concentration) was against Staphylococcus aureus (I.Z.-23mm) was screened. Thus, S. xanthocarpum could be considered as a potential source of natural antimicrobials.


Keywords


Solanum xanthocarpum, Antimicrobial Activity, Organic Solvents.