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Antimicrobial Activity of Bauhinia variegata Leaves (Ethanolic) Extract


Affiliations
1 Department of Pharmacology, MES’s College of Pharmacy Sonai, Ahmednagar, (M.S.), 414105, India
2 Jawaharlal Nehru Cancer Hospital and Research Center, Bhopal, (M.P.), India
     

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Purpose: The antimicrobial activity of the 50 % methanolic extract of the leaves of Bauhinia variegata. (Leguminosae) was investigated in other to verify its claimed ethno medicinal use in the treatment of microbial infections.

Method: The antimicrobial activity of the extract was tested against standard strains and clinical isolates of some aerobic bacteria using the Agar well diffusion method. Commercial antibiotics were used as positive reference standards to determine the sensitivity of the strains.

Results: The extracts showed significant inhibitory activity against standard strains and clinical isolates of Staphylococcus aureus, clinical isolates of Bacillus subtilis and Streptococcus epidemidis. The MIC values obtained using the Agar-dilution test ranged from 5.0 mg/ml. - 10.0 mg/ml. Neither the concentrated extract nor its dilutions inhibited Esherichia coli, Pseudomonas aeruginosa and Shigella floxineri

Conclusion: The results demonstrate that the crude extract of the leaves of Bauhinia Variegata has a narrow spectrum of activity and suggest that it may be useful in the treatment of infections caused by Gram positive aerobic bacteria.


Keywords

Antimicrobial Activity, Bauhinia variegata, Methanol Extract.
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  • Antimicrobial Activity of Bauhinia variegata Leaves (Ethanolic) Extract

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Authors

S. M. Bairagi
Department of Pharmacology, MES’s College of Pharmacy Sonai, Ahmednagar, (M.S.), 414105, India
R. C. Agrawal
Jawaharlal Nehru Cancer Hospital and Research Center, Bhopal, (M.P.), India
Nitin Nema
Jawaharlal Nehru Cancer Hospital and Research Center, Bhopal, (M.P.), India

Abstract


Purpose: The antimicrobial activity of the 50 % methanolic extract of the leaves of Bauhinia variegata. (Leguminosae) was investigated in other to verify its claimed ethno medicinal use in the treatment of microbial infections.

Method: The antimicrobial activity of the extract was tested against standard strains and clinical isolates of some aerobic bacteria using the Agar well diffusion method. Commercial antibiotics were used as positive reference standards to determine the sensitivity of the strains.

Results: The extracts showed significant inhibitory activity against standard strains and clinical isolates of Staphylococcus aureus, clinical isolates of Bacillus subtilis and Streptococcus epidemidis. The MIC values obtained using the Agar-dilution test ranged from 5.0 mg/ml. - 10.0 mg/ml. Neither the concentrated extract nor its dilutions inhibited Esherichia coli, Pseudomonas aeruginosa and Shigella floxineri

Conclusion: The results demonstrate that the crude extract of the leaves of Bauhinia Variegata has a narrow spectrum of activity and suggest that it may be useful in the treatment of infections caused by Gram positive aerobic bacteria.


Keywords


Antimicrobial Activity, Bauhinia variegata, Methanol Extract.