Research Journal of Pharmacognosy and Phytochemistry

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Antiulcer Activity of Cassia mimosoides Bark Extract and Its Comparison with Ranitidine in Shay Rat


Affiliations
1 Deptt. of Pharmacy, Utkal University, Bhubaneswar,754004 Orissa, India
2 CPS, Mohuda, Berampur, Orissa, India
3 VNS Institute of Pharmacy, Bhopal, 462044(MP), India
     

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Methanolic extract of Cassia Mimosoides bark was tested for its anti gastric ulcer activity in shay rat model. Oral dose with 5mg/kg body weight of ranitidine was found complete absence of ulceration. The anti gastric ulcer activity of Cassia Mimosoides Methanolic extract 800mg/kg body weight was found equal to the effect produced by 5mg/kg Ranitidine in shay rat.


Keywords

Cassia mimosoides, Methanolic Extract, Free Acidity, Total Acidity, Peptic Activity
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  • Antiulcer Activity of Cassia mimosoides Bark Extract and Its Comparison with Ranitidine in Shay Rat

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Authors

P. K. Panda
Deptt. of Pharmacy, Utkal University, Bhubaneswar,754004 Orissa, India
V. J. Patro
CPS, Mohuda, Berampur, Orissa, India
P. K. Mohanty
VNS Institute of Pharmacy, Bhopal, 462044(MP), India
S. K. Panda
Deptt. of Pharmacy, Utkal University, Bhubaneswar,754004 Orissa, India
Y. A. Jaliwalla
VNS Institute of Pharmacy, Bhopal, 462044(MP), India

Abstract


Methanolic extract of Cassia Mimosoides bark was tested for its anti gastric ulcer activity in shay rat model. Oral dose with 5mg/kg body weight of ranitidine was found complete absence of ulceration. The anti gastric ulcer activity of Cassia Mimosoides Methanolic extract 800mg/kg body weight was found equal to the effect produced by 5mg/kg Ranitidine in shay rat.


Keywords


Cassia mimosoides, Methanolic Extract, Free Acidity, Total Acidity, Peptic Activity