Study of Antimicrobial Activity of Canarium strictum Gum Resin

Canarium strictum Roxb. (Burseraceae) is used in the traditional Ayurvedic medicine under the name Raladhupa and black dammar resin. The isolation of compound A and compound B were carried out from chloroform extract by counter current distribution method. The purity of each compound was estimated by using Thin Layer Chromatography. The preliminary phytochemical screening of each compounds showed the presence of triterpenoid. The compound A and Compound B were investigated for antimicrobial (antibacterial and antifungal) activity by using cup plate method or diffusion agar method. The results obtained shows that compound A and compound B possess broad-spectrum antimicrobial activity at concentration of 100μg/ml. The inhibitory effect of each compound is very close and identical in magnitude for Gram- positive, Gram-negative bacteria and fungi.