Research Journal of Pharmacognosy and Phytochemistry

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Vitex negundo Linn; a Review on Its Ethnobotany, Phytochemical and Pharmacological Profile


Affiliations
1 National Institute of Ayurvedic Pharmaceutical Research, Patiala-147001, Punjab, India
2 School of Pharmaceutical Sciences, Shobhit University, Meerut, UP, India
3 National Institute of Ayurvedic Pharmaceutical Research, Patiala –147001, Punjab, India
     

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Vitex negundo Linn. is an large shrubs or small trees which is used in several traditional medicines to cure various diseases. This shrub has been known to posses hepatoprotective, antioxidant, anti-inflammatory, analgesic and antifungal activity. A wide range of chemical compounds including polyphenolic, terpenoids , glycosidic iridoids and alkaloids are present in this shrubs. Vitegnoside, negundoside, agunside, 5,3- dihydroxy-7,8,4-trimethoxy flavanone, 7,8-dimethyl herbacetin 3- rhamnoside etc. have been isolated from this plant. The presented review summarizes the information concerning the botany, ethnopharmacology, phytpchemistry, biological activity and toxicity of the Vitex negundo shrubs.


Keywords

Vitex negundo Linn, Antioxidant, Phytpchemistry, Antiinflammatory, Toxicity.
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  • Vitex negundo Linn; a Review on Its Ethnobotany, Phytochemical and Pharmacological Profile

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Authors

A. K. Meena
National Institute of Ayurvedic Pharmaceutical Research, Patiala-147001, Punjab, India
Uttam S. Niranjan
School of Pharmaceutical Sciences, Shobhit University, Meerut, UP, India
A. K. Yadav
School of Pharmaceutical Sciences, Shobhit University, Meerut, UP, India
Brijendra Singh
School of Pharmaceutical Sciences, Shobhit University, Meerut, UP, India
A. K. Nagaria
School of Pharmaceutical Sciences, Shobhit University, Meerut, UP, India
A. Gaurav
School of Pharmaceutical Sciences, Shobhit University, Meerut, UP, India
M. M. Rao
National Institute of Ayurvedic Pharmaceutical Research, Patiala –147001, Punjab, India

Abstract


Vitex negundo Linn. is an large shrubs or small trees which is used in several traditional medicines to cure various diseases. This shrub has been known to posses hepatoprotective, antioxidant, anti-inflammatory, analgesic and antifungal activity. A wide range of chemical compounds including polyphenolic, terpenoids , glycosidic iridoids and alkaloids are present in this shrubs. Vitegnoside, negundoside, agunside, 5,3- dihydroxy-7,8,4-trimethoxy flavanone, 7,8-dimethyl herbacetin 3- rhamnoside etc. have been isolated from this plant. The presented review summarizes the information concerning the botany, ethnopharmacology, phytpchemistry, biological activity and toxicity of the Vitex negundo shrubs.


Keywords


Vitex negundo Linn, Antioxidant, Phytpchemistry, Antiinflammatory, Toxicity.