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Inhibitory Effects of Ethanolic Extract of Physalis minima on Amylase, Lipase and Alpha Glucosidase


Affiliations
1 Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh-508 001, India
2 Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh-508 001, India
     

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The aim of the present study was to assess the effects of ethanolic extract of Physalis minima on the amylase, lipase and alpha glucosidase activity in vitro. Powder of whole plant of Physalis minima was extracted in ethanol and the extract was assayed for the measurement of inhibitory effects on activities of enzymes. The extracts rich in bioactive phytochemicals showed inhibitory activity on the amylase, lipase and alpha glucosidase, thus suggesting that extract might be useful in the treatment to limit dietary fat and glucose absorption and the accumulation of fat in adipose tissue. The extracts of Physalis minima may be safe, natural and cost effective for reducing fat and glucose absorption.

Keywords

Physalis minima, Amylase, Lipase, Alpha Glucosidase.
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  • Inhibitory Effects of Ethanolic Extract of Physalis minima on Amylase, Lipase and Alpha Glucosidase

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Authors

S. N. Raju
Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh-508 001, India
D. Sathis Kumar
Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh-508 001, India
Otilia Banji
Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh-508 001, India
David Banji
Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh-508 001, India
P. Yogeswaran
Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh-508 001, India
D. Narender Prasad
Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh-508 001, India
A. Harani
Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh-508 001, India

Abstract


The aim of the present study was to assess the effects of ethanolic extract of Physalis minima on the amylase, lipase and alpha glucosidase activity in vitro. Powder of whole plant of Physalis minima was extracted in ethanol and the extract was assayed for the measurement of inhibitory effects on activities of enzymes. The extracts rich in bioactive phytochemicals showed inhibitory activity on the amylase, lipase and alpha glucosidase, thus suggesting that extract might be useful in the treatment to limit dietary fat and glucose absorption and the accumulation of fat in adipose tissue. The extracts of Physalis minima may be safe, natural and cost effective for reducing fat and glucose absorption.

Keywords


Physalis minima, Amylase, Lipase, Alpha Glucosidase.