Research Journal of Pharmacognosy and Phytochemistry

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Anti-Lipidemic Effect of Alternanthera sessilis Linn in Diabetic Rats


Affiliations
1 Department of Biochemistry, PSG College of Arts and Science, Coimbatore- Pin 641014, Tamil Nadu, India
2 Department Of Biochemistry, PSG College of Arts and Science, Coimbatore- Pin 641014, Tamil Nadu, India
     

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Cardiovascular diseases are becoming an increasing problem worldwide. Hypercholesterolemia has been implicated as the major cause for Coronary Heart Diseases. Based on its high Flavonoid content of the herbal plant Althernanthera sessilis was tested for antihyperlipidemic property. It showed significant decreases in the levels of serum Total Cholesterol(TC), Triglyceride(TG), Low density lipoprotein(LDL), Very low density lipoprotein(VLDL) and significant increase in the level of High density lipoprotein(HDL) when administered orally for 28 days to alloxan induced hyperlipidemic rats at a dose of 150,300,450 mg/kg.
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  • Anti-Lipidemic Effect of Alternanthera sessilis Linn in Diabetic Rats

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Authors

A. Rohini
Department of Biochemistry, PSG College of Arts and Science, Coimbatore- Pin 641014, Tamil Nadu, India
D. Victor Arokia Doss
Department Of Biochemistry, PSG College of Arts and Science, Coimbatore- Pin 641014, Tamil Nadu, India

Abstract


Cardiovascular diseases are becoming an increasing problem worldwide. Hypercholesterolemia has been implicated as the major cause for Coronary Heart Diseases. Based on its high Flavonoid content of the herbal plant Althernanthera sessilis was tested for antihyperlipidemic property. It showed significant decreases in the levels of serum Total Cholesterol(TC), Triglyceride(TG), Low density lipoprotein(LDL), Very low density lipoprotein(VLDL) and significant increase in the level of High density lipoprotein(HDL) when administered orally for 28 days to alloxan induced hyperlipidemic rats at a dose of 150,300,450 mg/kg.