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In Vitro Licicidal Activity of Different Roots and Leaves Extract of Enicostema axillare (Gentianaceae)


Affiliations
1 Government College of Pharmacy, Kathora Naka, Amravati- 444 604 (M.S.), India
2 Government College of Pharmacy, Amravati 444604(M.S.), India
3 MIT College of Pharmacy, Kothrud, Pune, India
     

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Enicostema axillare is well known for its anthelmintic and bacterial activity. In present study dried leaves and ischolar_mains of Enicostema axillare were subjected to exhaustic sequential extraction with four solvent i.e.-hexane, chloroform, methanol and distilled water respectively. All four extracts were studied for in vitro licicidal activity using goat-lice Damalinia caprae (Trichodectidae) as experimental organism. Only n-hexane and chloroform fractions showed statistically significant licicidal activity (p value <0.001, n = 5). Decrease in mean time required to kill the lice was observed at concentration 1% w/w and 10% w/w when compared to 1% lindane solution.


Keywords

Enicostema axillare Leaves and Roots, Licicidal Activity.
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  • In Vitro Licicidal Activity of Different Roots and Leaves Extract of Enicostema axillare (Gentianaceae)

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Authors

P. B. Aswar
Government College of Pharmacy, Kathora Naka, Amravati- 444 604 (M.S.), India
S. S. Khadabadi
Government College of Pharmacy, Amravati 444604(M.S.), India
B. S. Kuchekar
MIT College of Pharmacy, Kothrud, Pune, India
R. Dhage
Government College of Pharmacy, Amravati 444604(M.S.), India
S. P. Deshmukh
Government College of Pharmacy, Amravati 444604(M.S.), India

Abstract


Enicostema axillare is well known for its anthelmintic and bacterial activity. In present study dried leaves and ischolar_mains of Enicostema axillare were subjected to exhaustic sequential extraction with four solvent i.e.-hexane, chloroform, methanol and distilled water respectively. All four extracts were studied for in vitro licicidal activity using goat-lice Damalinia caprae (Trichodectidae) as experimental organism. Only n-hexane and chloroform fractions showed statistically significant licicidal activity (p value <0.001, n = 5). Decrease in mean time required to kill the lice was observed at concentration 1% w/w and 10% w/w when compared to 1% lindane solution.


Keywords


Enicostema axillare Leaves and Roots, Licicidal Activity.