Research Journal of Pharmacognosy and Phytochemistry

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Visible Spectrophotometric Determination of Ferrum Phosphoricum in Homeopathic Formulations


Affiliations
1 Department of Pharma. Chemistry, Dr HLT College of Pharmacy, Kengal, Channapatna, Karnataka, India
2 Department of Pharmaceutical Chemistry, Dr HLT College of Pharmacy, Channapatna, Karnataka- 571502, India
     

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The present study deals with the determination of Ferrum Phophoricum and Ferrum metal in some Homeopathic formulations. The method is based on Fe3+ reduce to Fe2+ with hydroxyl ammonium chloride which react with the 1-10 phenanthroline in the pH range 3-5 to form an orange-red colour complex which shows the maximum absorbance at 518 nm. Beer's law is obeyed in the concentration range of 0.5-3mg/ml. Results of the analysis were validated statistically and by recovery studies. The Percentage label claim and Percentage recoveries estimated were close to 100% with low value of standard deviation and Percentage coefficient of variation.

Keywords

Ferrum Phosohoricum, Spectrophotometry, Fe,sup>2+ 1-10 Phenanthroline Complex.
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  • Visible Spectrophotometric Determination of Ferrum Phosphoricum in Homeopathic Formulations

Abstract Views: 242  |  PDF Views: 0

Authors

Syed Azhar Nizami
Department of Pharma. Chemistry, Dr HLT College of Pharmacy, Kengal, Channapatna, Karnataka, India
D. Ashok Kumar
Department of Pharmaceutical Chemistry, Dr HLT College of Pharmacy, Channapatna, Karnataka- 571502, India
S. C. Marihal
Department of Pharmaceutical Chemistry, Dr HLT College of Pharmacy, Channapatna, Karnataka- 571502, India

Abstract


The present study deals with the determination of Ferrum Phophoricum and Ferrum metal in some Homeopathic formulations. The method is based on Fe3+ reduce to Fe2+ with hydroxyl ammonium chloride which react with the 1-10 phenanthroline in the pH range 3-5 to form an orange-red colour complex which shows the maximum absorbance at 518 nm. Beer's law is obeyed in the concentration range of 0.5-3mg/ml. Results of the analysis were validated statistically and by recovery studies. The Percentage label claim and Percentage recoveries estimated were close to 100% with low value of standard deviation and Percentage coefficient of variation.

Keywords


Ferrum Phosohoricum, Spectrophotometry, Fe,sup>2+ 1-10 Phenanthroline Complex.