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Antimicrobial Investigation of Different Extracts of Dolichos lablab Beans


Affiliations
1 Dept. of Pharma. Chemistry, B. Pharmacy College, Rampura, Kakanpur, Godhara, Gujarat, India
2 N.G.S.M Institute of Pharm.Sciences, Paneer, Dearalaktte, Mangalore, India
3 Pharmacy College, Rampura, Kakanpur, Godhara, Panchmahal, Gujarat, India
     

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Increasing prevalence of multidrug resistant strains of microorganisms has initiated the exploration of alternate antimicrobial agent. Taking into account the medicinal importance of Dolichos Lablab (Fabaceae) in this respect, an attempt was made in the current study to investigate the antimicrobial potential of this plant. Antimicrobial activity of the ethanolic, petroleum ether, aqueous, chloroform, ethyl acetate and nhexane extracts of Dolichos Lablab beans were determined against various pathogenic bacteria and fungi. The extracts were tested against various bacteria like Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and fungi like Candida albicans by disk diffusion method. Minimum Inhibitory Concentration (MIC) values of each active extract were determined. It is concluded that n-Hexane and chloroform extract exhibited significant antimicrobial and antifungal activity.

Keywords

Dolichos Lablab, Antibacterial, Antifungal, Disk Diffusion Method.
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  • Antimicrobial Investigation of Different Extracts of Dolichos lablab Beans

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Authors

Akash P. Dahake
Dept. of Pharma. Chemistry, B. Pharmacy College, Rampura, Kakanpur, Godhara, Gujarat, India
Arun B. Joshi
N.G.S.M Institute of Pharm.Sciences, Paneer, Dearalaktte, Mangalore, India
Krunal M. Patel
Pharmacy College, Rampura, Kakanpur, Godhara, Panchmahal, Gujarat, India

Abstract


Increasing prevalence of multidrug resistant strains of microorganisms has initiated the exploration of alternate antimicrobial agent. Taking into account the medicinal importance of Dolichos Lablab (Fabaceae) in this respect, an attempt was made in the current study to investigate the antimicrobial potential of this plant. Antimicrobial activity of the ethanolic, petroleum ether, aqueous, chloroform, ethyl acetate and nhexane extracts of Dolichos Lablab beans were determined against various pathogenic bacteria and fungi. The extracts were tested against various bacteria like Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and fungi like Candida albicans by disk diffusion method. Minimum Inhibitory Concentration (MIC) values of each active extract were determined. It is concluded that n-Hexane and chloroform extract exhibited significant antimicrobial and antifungal activity.

Keywords


Dolichos Lablab, Antibacterial, Antifungal, Disk Diffusion Method.