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Cytotoxic Activity of Alphonsea sclerocarpa Bark Extract


Affiliations
1 Dept. of Pharmacognosy, Nalanda College of Pharmacy, Cherlapally, Nalgonda, Andrapradesh, India
     

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Invitro cytotoxic activity of Alphonsea sclerocarpa has been investigated by tryphan blue dye exclusion method at various concentration on Ehlirich Ascites Carcinoma cells. The ethanolic extracts of Alphonsea sclerocarpa has showed the significant cytotoxic property by inhibiting the dye exclusion was evaluated by comparing with standard 5- Fluorouracil. The preliminary study indicates the ethanolic extract of Alphonsea sclerocarpa has significant cytotoxic property and suggests for further investigation for its antitumor and anticarcinogenic function in different models.


Keywords

Alphonsea sclerocarpa, Cytotoxic Activity, EAC Cells, 5-Fluorouracil.
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  • Cytotoxic Activity of Alphonsea sclerocarpa Bark Extract

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Authors

Dasari Narendra Prasad
Dept. of Pharmacognosy, Nalanda College of Pharmacy, Cherlapally, Nalgonda, Andrapradesh, India

Abstract


Invitro cytotoxic activity of Alphonsea sclerocarpa has been investigated by tryphan blue dye exclusion method at various concentration on Ehlirich Ascites Carcinoma cells. The ethanolic extracts of Alphonsea sclerocarpa has showed the significant cytotoxic property by inhibiting the dye exclusion was evaluated by comparing with standard 5- Fluorouracil. The preliminary study indicates the ethanolic extract of Alphonsea sclerocarpa has significant cytotoxic property and suggests for further investigation for its antitumor and anticarcinogenic function in different models.


Keywords


Alphonsea sclerocarpa, Cytotoxic Activity, EAC Cells, 5-Fluorouracil.