Research Journal of Pharmacognosy and Phytochemistry

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In Vitro Anti-Fungal Activity of the Methanolic Extract of the Leaves Lagerstroemia parviflora (Roxb.)


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1 Dept. of Pharm. Technology, N.I.E.T., 19, Knowledge Park-II, Greater Noida, U.P. 201306, India
     

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The methanolic extract of the leaves of Lagerstroemia parviflora (Roxb) was tested for its Minimum Inhibitory Concentration (MIC) against different fungi belonging to Candida, Aspergillus and Penicillium species. Further, zones of inhibition produced by the crude extract against the fungal strains were measured and compared with those produced by standard antifungal agent Griseofulvin. The extract was proved that it was highly toxic against Candida albicans ATCC10231, Aspergillus thiogentalis MTCC 804, Penicillum notatum ATCC 6275, Penicillum funiculosum NCTC 287, and Penicillum citrinum MTCC 1256. The extract showed less toxicity against Aspergillus niger (ATCC 6275). The extract was found to be fungistatic in its action.

Keywords

Lagerstroemia parviflora, Antifungal, MIC, Leaves.
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  • In Vitro Anti-Fungal Activity of the Methanolic Extract of the Leaves Lagerstroemia parviflora (Roxb.)

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Authors

Sangita Kumari
Dept. of Pharm. Technology, N.I.E.T., 19, Knowledge Park-II, Greater Noida, U.P. 201306, India
Avijit Mazumder
Dept. of Pharm. Technology, N.I.E.T., 19, Knowledge Park-II, Greater Noida, U.P. 201306, India
Rupa Mazumder
Dept. of Pharm. Technology, N.I.E.T., 19, Knowledge Park-II, Greater Noida, U.P. 201306, India
Shilpa Pahwa
Dept. of Pharm. Technology, N.I.E.T., 19, Knowledge Park-II, Greater Noida, U.P. 201306, India

Abstract


The methanolic extract of the leaves of Lagerstroemia parviflora (Roxb) was tested for its Minimum Inhibitory Concentration (MIC) against different fungi belonging to Candida, Aspergillus and Penicillium species. Further, zones of inhibition produced by the crude extract against the fungal strains were measured and compared with those produced by standard antifungal agent Griseofulvin. The extract was proved that it was highly toxic against Candida albicans ATCC10231, Aspergillus thiogentalis MTCC 804, Penicillum notatum ATCC 6275, Penicillum funiculosum NCTC 287, and Penicillum citrinum MTCC 1256. The extract showed less toxicity against Aspergillus niger (ATCC 6275). The extract was found to be fungistatic in its action.

Keywords


Lagerstroemia parviflora, Antifungal, MIC, Leaves.