Research Journal of Pharmacognosy and Phytochemistry

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Analgesic Activity of Tamarindus indica


Affiliations
1 Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni (413736), Maharashtra, India
2 Department of Pharmacognosy, Pravara Rural College of Pharmacy, Loni (413736), Maharashtra, India
     

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Tamarindus indica (Caesalpiniaceae) bark is used in the treatment of pain traditionally, present work was undertaken to prove this scientifically by using suitable animal screening models as hot plate test and acetic acid induced writing test at the dose of 50 mg/kg, i.p. Petroleum ether extract showed significant increase in reaction time as compared to other extracts. Preliminary phytochemical test showed presence of sterols and triterpenes in the extract; hence these compounds might be responsible for analgesic activity.
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  • Analgesic Activity of Tamarindus indica

Abstract Views: 238  |  PDF Views: 0

Authors

N. S. Dighe
Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni (413736), Maharashtra, India
S. R. Pattan
Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni (413736), Maharashtra, India
S. A. Nirmal
Department of Pharmacognosy, Pravara Rural College of Pharmacy, Loni (413736), Maharashtra, India
R. S. Kalkotwar
Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni (413736), Maharashtra, India
V. M. Gaware
Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni (413736), Maharashtra, India
M. B. Hole
Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni (413736), Maharashtra, India

Abstract


Tamarindus indica (Caesalpiniaceae) bark is used in the treatment of pain traditionally, present work was undertaken to prove this scientifically by using suitable animal screening models as hot plate test and acetic acid induced writing test at the dose of 50 mg/kg, i.p. Petroleum ether extract showed significant increase in reaction time as compared to other extracts. Preliminary phytochemical test showed presence of sterols and triterpenes in the extract; hence these compounds might be responsible for analgesic activity.