Research Journal of Pharmacognosy and Phytochemistry

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In Vitro Cytotoxic Activity of Leaves of Abutilon indicum Linn. Against Ehrlich Ascites Carcinoma and Dalton’s Ascitic Lymphoma Cell Line


Affiliations
1 Department of Pharmacology, Bajiraoji Karanjekar College of Pharmacy, Sakoli, Dist. Bhandara. (M.S) 441802, India
2 Department of Pharmacology, Guru Ramdas Khalsa Institute of Science and Technology, Jabalpur (M.P), India
     

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Alcohol and aqueous extracts from the leaves of Abutilon indicum Linn. Were investigating for their cytotoxic activity against EAC and DLA cell line. Various concentrations (10-200μg/ml) of each extract were treated in trypan blue method. Which involved determination of number of dead cells/total 100 cells counted gives the percentage of cytotoxicity was calculated. Both the extract exhibited significant cytotoxic activity at higher concentration of 200μg/ml. Distilled water used as a control.


Keywords

Abutilon Indicum, Cytotoxic Activity, Ehrlich Ascites Carcinoma (EAC), Dalton’s Ascitic Lymphoma (DLA).
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  • In Vitro Cytotoxic Activity of Leaves of Abutilon indicum Linn. Against Ehrlich Ascites Carcinoma and Dalton’s Ascitic Lymphoma Cell Line

Abstract Views: 141  |  PDF Views: 0

Authors

A. V. Bondre
Department of Pharmacology, Bajiraoji Karanjekar College of Pharmacy, Sakoli, Dist. Bhandara. (M.S) 441802, India
S. C. Akare
Department of Pharmacology, Guru Ramdas Khalsa Institute of Science and Technology, Jabalpur (M.P), India
P. Mourya
Department of Pharmacology, Guru Ramdas Khalsa Institute of Science and Technology, Jabalpur (M.P), India
A. D. Wanjari
Department of Pharmacology, Guru Ramdas Khalsa Institute of Science and Technology, Jabalpur (M.P), India
P. S. Tarte
Department of Pharmacology, Guru Ramdas Khalsa Institute of Science and Technology, Jabalpur (M.P), India
G. V. Paunikar
Department of Pharmacology, Guru Ramdas Khalsa Institute of Science and Technology, Jabalpur (M.P), India

Abstract


Alcohol and aqueous extracts from the leaves of Abutilon indicum Linn. Were investigating for their cytotoxic activity against EAC and DLA cell line. Various concentrations (10-200μg/ml) of each extract were treated in trypan blue method. Which involved determination of number of dead cells/total 100 cells counted gives the percentage of cytotoxicity was calculated. Both the extract exhibited significant cytotoxic activity at higher concentration of 200μg/ml. Distilled water used as a control.


Keywords


Abutilon Indicum, Cytotoxic Activity, Ehrlich Ascites Carcinoma (EAC), Dalton’s Ascitic Lymphoma (DLA).