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Coccinia indica - A Phytopharmacological Review


Affiliations
1 Gorishankar Education society’s College of Pharmacy (D. Pharm) Limb, Satara, India-415015, India
2 Gourishankar Institute of Pharmaceutical Education & Research, Limb, Satara, India-415015, India
     

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Coccinia indica belonging to family Cucurbitaceae is distributed all over India, it is commonly known as Ivy gourd and the leaves, ischolar_mains, fruits and bark has been used for various disorders in traditional and folk medicine. The plant is used as cathartic, antispasmodic, expectorant, etc. The leaves are used as anthelmintic, antispasmodic, expectorant, and antiulcer. Fruits are used as laxative, antiemetic, anti-inflammatory, antileprotic. Roots are used as cathartic, antiarthritic, hypoglycemic. The plant is known to possess various active constituents like steroids, alkaloids, flavonoids, glycosides, tannins and Phenolic compounds. The plant is screened for hepatoprotective, antimicrobial, anthelmintic, antibacterial, anti-inflammatory, antioxidant and antiulcerogenic activity. The present review is therefore, an effort to give a detailed survey of the literature on the microscopical, phytochemical and pharmacological properties of Coccinia indica. This review supports all updated information on its phytochemical and pharmacological activities, traditional uses and scientific approach. Coccinia indica is one of the most important controversial and effective natural origin that has a tremendous future for research. The plant part contains important constituents and has been widely used for the treatment of large number of human ailments. The applicability of Coccinia indica is hidden and thus such things should be overcome through modern scientific concepts.

Keywords

Coccinia Indica, Traditional Uses, Phytoconstituents, Hepatoprotective Activity, Hypoglycemic Activity, Antioxidant Activity.
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  • Agrawal SS, Tamrakar BP. Clinically Used Herbal Drugs, Edn 1st, Ahuja Publishing House 2005, 314-317.
  • Kirtikar KR, Basu BD. Indian Medicinal Plants, Edn 2, Vol. II, Dehradun 1987, 1151-1154.
  • S. Syed et al. investigated antimicrobial activity of fruit extract of the Cocconia indica. African Journal of Biotechnology, (2009), 8(24):7073-7076.
  • http://en.wikipedia.org/wiki/Caccia_grandis
  • Niranjan S. studied Pharmacognostical studies of Coccinia indica Weight & Arn leaves. International Journal of Pharma Research & Development. 2003, 2(10): 15-24.
  • Baghel SS, Dangi S, Soni P, Singh P, Shivare Y. Acute toxicity study of Aqueous Extract of Coccinia indica ischolar_mains, Asian Journal Research Pharmaceutical Sciences. 2011; 1(1): 23-25
  • Vaishnav MM, Jain P, Gupta KRE. Coccinioside-K, terpenoid saponin from Coccinia indica. Oriental J. Chem., 2001, 17(3):465-468.
  • Vaishnav MM, Gupta KR. Ombuin 3-O-arabinofuranoside from Coccinia indica. Fitoterapia, (1996) 67(1): 80.
  • Vaishnav MM, Gupta KR (1995). A new saponin from Coccinia indica ischolar_mains. Fitoterapia, 66(6): 546-547.
  • Khastgir HN, Choudhuri SN, Gupta PS. Roots of Coccinia indica. J. Indian Chem. Soc., (1958) 35: 905-906.
  • Kundu S, Ray AB. Chemical examination of Coccinia indica fruits. J. Indian Chem. Soc., (1987) 64(12): 776-777.
  • Basu K, Ghosh BK. Chemical investigation of Coccinia indica. Transactions of the Bose Res. Inst. (Calcutta). (1972), 35(2): 43- 44.
  • Bhakuni DS, Srivastava SN, Sharma VN, Kaul KN. Chemical examination of the fruits of Coccinia indica. J. Sci. Ind. Res., Section B: Phys. Sci., (1962), 21B: 237-238.
  • Qudrat-i-Khuda M, Khaleque KA, Miah MAW. Chemical investigations on Cephalandra indica. I. Constituents of dry aerial parts. Dacca Sci. Res., (Dacca, Pakistan), (1965), 2(1/2): 27-231.
  • Dhargalkar IM, Guha SK. Nutritional values of Indian vegetables. J. Proc. Inst. Chemists, (1959), (31): 109-112.
  • Rahman M, Mahbubur C, Tofail A, Mosihuzzaman M. Analysis of water- and alkali-soluble polysaccharides of Coccinia indica (Telakucha) plant. J. Bangladesh Chem. Soc., (1990), 3(2): 199- 204. 17. Syed Zeenat Shaheen; Krisna Bola; Kandukuri Vasu; MA Singracharya. African Journal of Biotechnology., 2008, (8), 7073-7076.
  • Shivhare Y, Soni P, Singh P, Dangi S, Baghel1 S. Evaluation of Anthelmintic Activity of Coccinia indica (fruits). J. Chem. Pharm. Res., 2011, 3(1):488-491.
  • S. P. Dhanabal, C. K. Koate, M. Ramanathan, K. Elango, B. Suresh. The hypoglycemic activity of Coccinia indica Wight & Arn. and its influence on certain biochemical parameters. Indian J Pharmacol. August 2004, Vol 36, Issue 4, 244-250.
  • Manish Gunjan, Goutam K. Jana, A. K Jha, Umashanker Mishra. Pharmacognostic and antihyperglycemic study of Coccinia indica. International Journal of Phytomedicine 2 (2010) 36-40.
  • Eliza Jose, P.T.A Usha, Evaluation of antidiabetic efficacy of Coccinia indica in rats. Indian J. Anim. Res., 2010, 44 (3) : 168 - 172.
  • Gupta SS. Pituitary diabetes III. Effect of indigenous antidiabetic drugs against the acute hyperglycemic response of anterior pituitary extract in gluose fed albino rats. Indian J. Med. Res., (1963), 51(4): 716-724.
  • Preeth. Manoharan, Shobana. John, Upendarrao. Golla, Dr. Thangathirupathi. Anti-ulcer effect of Coccinia grandis (linn.) On pylorus ligated (albino) rats. International Journal of Pharma Research and Development. 2010,PUB,ARTI,VOV-2,ISSUE- 5,JULY,001-009.
  • Umbreen farrukh, huma shareef, shaukat mahmud, Syed ayub ali and ghazala h. Rizwani antibacterial activities of Coccinia grandis L. Pak. J. Bot., 40(3): 1259-1262, 2008.
  • Arshad Hussain, Shadma Wahab, Iffat Zarin, M.D. Sarfaraj Hussain. Antibacterial Activity of the Leaves of Coccinia indica (W. and A) W of India. Advances in Biological Research 4 (5): 241-248, 2010
  • Deshpande SV., Patil MJ., Parmar KK., Daswadkar SC. and Khodade RB. A study on antioxidant activity of fruit extracts of coccinia grandis L.voigt. Int. J. Drug Res. Tech. 2011, Vol. 1 (1), 69-72
  • Shakti Prasad Pattanayak, Priyashree Sunita. In vivo antitussive activity of Coccinia grandis against irritant aerosol and sulfur dioxide-induced cough model in rodents. Bangladesh J Pharmacol 2009; 4: 84-87.
  • Shivaji P Gawade, Chandrashekar Rao M.V. Antihepatotoxic Activities of Ci Compound: ß Sitosterol Isolated from Fruits and Leaves of Coccinia indica. Ind J Pharm Edu Res, Jan-Mar, 2012, Vol 46, Issue 1, 4-8.
  • Niazi J, Singh P, Bansal Y, Goel RK (2009). Anti-inflammatory, analgesic and antipyretic activity of aqueous extract of fresh leaves of Coccinia indica. Inflammopharmacol, 17(4): 239-244.

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  • Coccinia indica - A Phytopharmacological Review

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Authors

VN Raje
Gorishankar Education society’s College of Pharmacy (D. Pharm) Limb, Satara, India-415015, India
AV Yadav
Gourishankar Institute of Pharmaceutical Education & Research, Limb, Satara, India-415015, India
PA Shelar
Gourishankar Institute of Pharmaceutical Education & Research, Limb, Satara, India-415015, India

Abstract


Coccinia indica belonging to family Cucurbitaceae is distributed all over India, it is commonly known as Ivy gourd and the leaves, ischolar_mains, fruits and bark has been used for various disorders in traditional and folk medicine. The plant is used as cathartic, antispasmodic, expectorant, etc. The leaves are used as anthelmintic, antispasmodic, expectorant, and antiulcer. Fruits are used as laxative, antiemetic, anti-inflammatory, antileprotic. Roots are used as cathartic, antiarthritic, hypoglycemic. The plant is known to possess various active constituents like steroids, alkaloids, flavonoids, glycosides, tannins and Phenolic compounds. The plant is screened for hepatoprotective, antimicrobial, anthelmintic, antibacterial, anti-inflammatory, antioxidant and antiulcerogenic activity. The present review is therefore, an effort to give a detailed survey of the literature on the microscopical, phytochemical and pharmacological properties of Coccinia indica. This review supports all updated information on its phytochemical and pharmacological activities, traditional uses and scientific approach. Coccinia indica is one of the most important controversial and effective natural origin that has a tremendous future for research. The plant part contains important constituents and has been widely used for the treatment of large number of human ailments. The applicability of Coccinia indica is hidden and thus such things should be overcome through modern scientific concepts.

Keywords


Coccinia Indica, Traditional Uses, Phytoconstituents, Hepatoprotective Activity, Hypoglycemic Activity, Antioxidant Activity.

References