Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Gastroprotective Activity of Avipathi Choornam


Affiliations
1 Department of Pharmacology, R.V.S. College of Pharmaceutical Sciences, Sulur, Coimbatore, Tamil Nadu, India
     

   Subscribe/Renew Journal


Ayurveda is the one of the most noted system of medicine in the world. The term Ayurveda in Sanskrit consist of two words: Ayur meaning life and Veda meaning science, thus Ayurveda is the science of life. Avipathi Choornam is an ayurvedic medicine and contains rhizomes of Zingiber officinale; fruits of Piper Nigrum, Piper longum, Embelia ribes, Emblica officinalis, seeds of Elettaria cardamomum and leaves of Cinnamomum zeyalanicum and it are useful for the treatment of peptic ulcer. Peptic ulcer is a break in the lining of the stomach or duodenum. The gastroprotective activity of Avipathi Choornam was performed by the screening of antiulcer activity by ethanol induced gastric ulcer and screening of gastroprotective effect by Pylorus ligation method. The toxicity study shows the safety nature of Avipathi Choornam and the results obtained shows that it is a good and safe therapeutic agent for ulcer treatment.

Keywords

Ayurveda, Avipathi Choornam, Peptic Ulcer, Ethanol, Pylorus Ligation.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Waugh, Anne. Ross and Wilson Anatomy and Physiology in Health and Illness, 11th Edition. Churchill Livingstone, Page. 281-292, 2010.
  • Anne M. R. Agur; Moore, Keith L. Essential Clinical Anatomy (Point (Lippincott Williams and Wilkins). Hagerstown, MD: Lippincott Williams and Wilkins. Page.150, 2007.
  • David.E.Golan, Principles of Pharmacology, The Patho physiologic basis of Drug therapy, 2nd Edition, Page.811-817, 2000.
  • Chaturvedi A, Kumar MM, Bhawani G, Chaturvedi H, Kumar M, Goel KR. Effect of ethanolic extract of Eugenia jambolana seeds on gastric ulceration and secretion in rats. Indian J Physiol Pharmacol, 51(2): 2007, 131-140.
  • Rubin E, Gorstein F, Rubin R, Schwarting R, Strayer D. Clinico Pathologic Foundations of Medicine. 4th Ed. United State of America: Lippincott Williams and Wilkins, Page 680-3, 2005.
  • Kokate.C.K, Purohit.A.P, Gokhale.S.H, Text book of Pharmacognosy, Nirali Prakashan Pub Pvt Ltd. Ansari S.H, Page 3-7, 2000.
  • Vinod. D. Rangari, Text book of Pharmacognosy and Phytochemistry, Vol-1, P.No.6-27, 2000.
  • Vogel HG. Drug Discovery and Evaluation. 2nd Edition. New York: Springer-Verlag Berlin Heidelberg, Page 867–872, 2002.
  • Jamal A, Farah, Siddiqui A, Aslam M, Javed K, Jafri MA, Antiulcerogenic activity of Eletttaria cardamomum Maton and Amomum subulatum Roxb. Seeds. Indian Journal of Traditional Knowledge, 4(3): 2005, 298-302.
  • Tripathi KD. Essentials of Medical Pharmacology. 5thed. New Delhi: Jaypee Brothers Medical Publishers (P) Ltd Page.597, 2003.
  • Jamal A, Farah, Siddiqui A, Aslam M, Javed K, Jafri MA, Antiulcerogenic activity of Eletttaria cardamomum Maton and Amomum subulatum Roxb. Seeds. Indian Journal of Traditional Knowledge, 4(3): 2005, 298-302.
  • Maggi CA, Capsaicin-sensitive nerves in the gastrointestinal tract. Arch Int Pharmocodyn, 303: 1990, 157-166.
  • Rafatulla S, Tariq M, Alyahya MA. Evaluation of Turmeric (Curcuma Longa) for gastric and duodenal antiulcer activity in rats. J Ethnopharmacol, 29: 1990, 25-34.
  • Sumbul S, Ahmad MA, Mohd A, et al Role of Phenolic compounds in peptic ulcer: An Overview, J Pharm Bioallied Sci, 3(3): 2011, Page 361.
  • Khushtar M, Kumar V, Javed K, Bhandari U et al Protective Effect of Ginger oil on Aspirin and Pylorus Ligation-Induced Gastric Ulcer model in Rats. Indian J Pharm Sci.71 (5): 2009, 554-8.

Abstract Views: 1299

PDF Views: 0




  • Gastroprotective Activity of Avipathi Choornam

Abstract Views: 1299  |  PDF Views: 0

Authors

D. Benito Johnson
Department of Pharmacology, R.V.S. College of Pharmaceutical Sciences, Sulur, Coimbatore, Tamil Nadu, India
C. Senthil Kumar
Department of Pharmacology, R.V.S. College of Pharmaceutical Sciences, Sulur, Coimbatore, Tamil Nadu, India
C. Glince Raphael
Department of Pharmacology, R.V.S. College of Pharmaceutical Sciences, Sulur, Coimbatore, Tamil Nadu, India
R. Venkatnarayanan
Department of Pharmacology, R.V.S. College of Pharmaceutical Sciences, Sulur, Coimbatore, Tamil Nadu, India
Siraj Kattupparuthi
Department of Pharmacology, R.V.S. College of Pharmaceutical Sciences, Sulur, Coimbatore, Tamil Nadu, India

Abstract


Ayurveda is the one of the most noted system of medicine in the world. The term Ayurveda in Sanskrit consist of two words: Ayur meaning life and Veda meaning science, thus Ayurveda is the science of life. Avipathi Choornam is an ayurvedic medicine and contains rhizomes of Zingiber officinale; fruits of Piper Nigrum, Piper longum, Embelia ribes, Emblica officinalis, seeds of Elettaria cardamomum and leaves of Cinnamomum zeyalanicum and it are useful for the treatment of peptic ulcer. Peptic ulcer is a break in the lining of the stomach or duodenum. The gastroprotective activity of Avipathi Choornam was performed by the screening of antiulcer activity by ethanol induced gastric ulcer and screening of gastroprotective effect by Pylorus ligation method. The toxicity study shows the safety nature of Avipathi Choornam and the results obtained shows that it is a good and safe therapeutic agent for ulcer treatment.

Keywords


Ayurveda, Avipathi Choornam, Peptic Ulcer, Ethanol, Pylorus Ligation.

References