In-Vitro Anthelmintic Evaluation of Polyherbal Formulation:Krumighattini Tablet

Ayurveda has abundant collection of effective formulations against diseases. The polyherbal formulation contains Vernonia anthelmintica, Curcuma longa, Piper longum, Mallotus philippinensis, Operculina turpethum, Terminalia chebula, Butea monosperma, and Red ochre. The present study deals with anthelmintic evaluation of ayurvedic formulation. Various concentrations of polyherbal formulation (10 mg/ml, 20 mg/ml and 30 mg/ml) in 50 ml of normal saline were taken. The results were compared with standard albendazole (10mg/ml, 20mg/ml and 30 mg/ml) and control was taken as normal saline (0.9% NaCl). The results were expressed in terms of time in minutes for the paralysis and time of death of the worms. Paralysis and death time were analyzed using one way ANOVA analysis using Graph pad prism 2.01 Software. The study indicates that polyherbal formulation shows more potent anthelmintic activity than standard reference.