Prescribing Trends of Antidiabetic Fixed Dose Combinations in a Rural Tertiary Care Teaching Hospital in Central India:An Observational, Cross-Sectional Study

Objective: To assess prescribing trends of Fixed dose combination antidiabetics in Diabetes Mellitus patients.

Materials and Methods: An observational, cross-sectional study was carried out in the Medicine OPD of AVBRH, Sawangi(M), Wardha. A total of 500 Diabetes Mellitus Patients were selected for the study after fulfilling the inclusion/exclusion criteria.

Results: Out of 500 patients 484 patients were of type-II DM in whom 5 FDCs were prescribed. Maximum prescribed FDCs were of Metformin and sulfonylurea Metformin + Glimepiride (n=74) and Metformin + Glipizide (n=37). Following FDCs were Metformin + Voglibose (n=52), Glimepiride + Pioglitazone (n=18) and least prescribed was Metformin+ Glimepiride + Voglibose (n=10). All the drugs were prescribed by brand names. Total of 191 patients (39.46%) were prescribed Antidiabetic FDCs.

Conclusion: All Antidiabetic FDCs prescribed were rational. FDCs in Antidiabetics are useful in combination therapy for increasing patient compliance and achieving euglycemia more effectively.