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Preparation of Novel Biocompatible Honey Hydrogel with Turmaric and Aloe vera


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1 Rajarambapu College of Pharmacy, Kasegaon. Tal-Walwa, Dist Sangli, Maharashtra, India
     

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There is an ever-present need for non-allergenic antibacterial and antifungal wound dressing with a superior healing property for chronic ulcers. Among the entire modern wound healing dressings, hydrogel has a good capacity to donate moisture or absorb exudate and thereby providing a moist environment to facilitate wound healing process and at the same time protect the wound too. In the present study, povidne iodine loaded acrylamide based biocompatible biodegradable hydrogel dressings incorporating alginate, chitosan and gelatin showed good fluid absorbance capacity. The addition of honey showed improved tensile strength and moisture absorbance capacity of the hydrogel sponge. Addition of turmeric and aloe vera give additional wound healing properties. Chitosan and Alginate films with different Aloe vera contents (5, 15, 25 and 35%) and turmeric contents (5, 15, 25 and 35%) were prepared and its properties evaluated in terms of thickness, transparency, swelling behavior and in vitro degradation.

Keywords

Chitosan, Hydrogel, Aloe vera, Turmeric.
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  • Preparation of Novel Biocompatible Honey Hydrogel with Turmaric and Aloe vera

Abstract Views: 335  |  PDF Views: 6

Authors

Rohan R. Vakhariya
Rajarambapu College of Pharmacy, Kasegaon. Tal-Walwa, Dist Sangli, Maharashtra, India
Rutuja R. Shaha
Rajarambapu College of Pharmacy, Kasegaon. Tal-Walwa, Dist Sangli, Maharashtra, India
Archana R. Dhole
Rajarambapu College of Pharmacy, Kasegaon. Tal-Walwa, Dist Sangli, Maharashtra, India
C. S. Magdum
Rajarambapu College of Pharmacy, Kasegaon. Tal-Walwa, Dist Sangli, Maharashtra, India

Abstract


There is an ever-present need for non-allergenic antibacterial and antifungal wound dressing with a superior healing property for chronic ulcers. Among the entire modern wound healing dressings, hydrogel has a good capacity to donate moisture or absorb exudate and thereby providing a moist environment to facilitate wound healing process and at the same time protect the wound too. In the present study, povidne iodine loaded acrylamide based biocompatible biodegradable hydrogel dressings incorporating alginate, chitosan and gelatin showed good fluid absorbance capacity. The addition of honey showed improved tensile strength and moisture absorbance capacity of the hydrogel sponge. Addition of turmeric and aloe vera give additional wound healing properties. Chitosan and Alginate films with different Aloe vera contents (5, 15, 25 and 35%) and turmeric contents (5, 15, 25 and 35%) were prepared and its properties evaluated in terms of thickness, transparency, swelling behavior and in vitro degradation.

Keywords


Chitosan, Hydrogel, Aloe vera, Turmeric.