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Antipsoriatic Activity of Gel Containing Methylsulphonylmethane Powder and Seed Oil of Pongamia pinnata Linn.


Affiliations
1 LNBC Institute of Pharmacy, Raigaon Satara, Maharashtra 415020, India
2 Department of Pharmacology, Adarsh College of Pharmacy Vita Dist Sangli, India
     

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To develop gel using Methylsulphonylmethane powder and seed oil of Pongamia pinnata Linn. to minimize side effects of current therapy. All prepared formulations were evaluated for pH, Viscosity, spradability, Extrudability. The release of optimized batch was carried out using Cellophane membrane into Phosphate buffer 6.8 at 37°C. The Characterization was carried out by using FTIR, DSC, SEM analysis. In-vtro & In-vivo activities were performed by using HaCaT Cell line and Mouse tail model respectively.

Keywords

Psoriasis, Orthokeratosis, Pongamia pinnata, Methylsulphonylmethane.
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  • Misal G., Dixit. Gulkari V, Formulation and evaluation of herbal gel, Indian journal of Natural Products and Resources, 2012; 3(4): 501-506.
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  • Misal G, Dixit, Gulkari V, 2012, Formulation and evaluation of herbal gel, Indian journal of Natural Products and Resources, 2012; 3(4):501-506.

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  • Antipsoriatic Activity of Gel Containing Methylsulphonylmethane Powder and Seed Oil of Pongamia pinnata Linn.

Abstract Views: 200  |  PDF Views: 0

Authors

Salunke Pradnya Balasaheb
LNBC Institute of Pharmacy, Raigaon Satara, Maharashtra 415020, India
Patil Sandeep Balvant
Department of Pharmacology, Adarsh College of Pharmacy Vita Dist Sangli, India
A. T. Kadam
LNBC Institute of Pharmacy, Raigaon Satara, Maharashtra 415020, India

Abstract


To develop gel using Methylsulphonylmethane powder and seed oil of Pongamia pinnata Linn. to minimize side effects of current therapy. All prepared formulations were evaluated for pH, Viscosity, spradability, Extrudability. The release of optimized batch was carried out using Cellophane membrane into Phosphate buffer 6.8 at 37°C. The Characterization was carried out by using FTIR, DSC, SEM analysis. In-vtro & In-vivo activities were performed by using HaCaT Cell line and Mouse tail model respectively.

Keywords


Psoriasis, Orthokeratosis, Pongamia pinnata, Methylsulphonylmethane.

References