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Antipsoriatic Activity of Gel Containing Methylsulphonylmethane Powder and Seed Oil of Pongamia pinnata Linn.
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To develop gel using Methylsulphonylmethane powder and seed oil of Pongamia pinnata Linn. to minimize side effects of current therapy. All prepared formulations were evaluated for pH, Viscosity, spradability, Extrudability. The release of optimized batch was carried out using Cellophane membrane into Phosphate buffer 6.8 at 37°C. The Characterization was carried out by using FTIR, DSC, SEM analysis. In-vtro & In-vivo activities were performed by using HaCaT Cell line and Mouse tail model respectively.
Keywords
Psoriasis, Orthokeratosis, Pongamia pinnata, Methylsulphonylmethane.
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