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Important Uses of Amalaki (Emblica officinalis) in Indian System of Medicine with Pharmacological Evidence


Affiliations
1 Central Ayurveda Research Institute for Hepatobiliary Disorders, Bhubaneswar, Odisha, India
2 Gopabandhu Ayurveda Mahavidyalaya, Puri, Odisha, India
     

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Emblica officinalis (syn. Phyllanthus emblica L.) is commonly known as Indian gooseberry. It has been extensively used & popularized because of its therapeutic properties having vitamin C, minerals and amino acids. The plant is used for medicinal purposes. The fruit apart from all parts of Emblica officinalis has been in nait in Ayurveda as a potent rejuvenator since days long. Various pharmaceutical properties of Emblica officinalis has been evinced previously embodying anti-oxidant, Immunomodulatory, anti-inflammatory, analgesic and antipyretic, antimicrobial, hepatoprotective, antitumor and antiulcerogenic activities either in combined formulation or Emblica officinalis proper. It is our expeditious exigencyto delve into the medicinal values of Emblica officinalis at molecular level with the succor of techniques of biotechnology though Research in medicinal plants has gained much more momentum.

Keywords

Amalaki, Gooseberry, Emblica officinalis, Pharmacological Activities, Hepatoprotective, Immunomodulatory, Antiulcerogenic.
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  • Newman DJ, Cragg GM, Sander KM. The influence of natural products upon drug discovery. Natural product Res 2000; 17: 215-234.
  • Cragg GM, byod MR, Khanna R, Mays TD, Mazan KD, Newman DJ, Sausvile EA. International Collaboration in drug discovery and development, the NCT experience. Pure Appl. Chem 1999; 71:1619-1633.
  • Gislene GF, Juliana L, Paulo CF, Giluliana LS. Antibacterial activity of plant extracts and phytochemicals on antibiotic Resistant Bacteria. Brazilian Journal of Microbiology 2000; 31: 247-256.
  • Ghani A, Medicinal Plants of Bangladesh with chemical constituents and uses Asiatic Society of Bangladesh,
  • Sharma Rohit, Gulab S. Thakur, Bhagwan S. Sanodiya, Ashish Savita, Mukeshwar Pandey, Anjana Sharma and Prakash S. Bisen. Therapeutic Potential of Calotropisprocera: A giant milkweed. IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) ISSN: 2278-3008. Volume 4, Issue 2 (Nov. – Dec. 2012), PP 42-57.
  • Kirtikar KR, Basu BD, Idian Medicinal Plants, Vol-3, 1935, Page-2222
  • A. Ganesan R. Identification, distribution and conservation of Phyllanthus indofischeri, another source of Indian gooseberry. CurrSci 2003; 84:1515-1518. B Sangeetha N, Mercy S, Kavitha M, Selvaraj D, Sathishkumar R, Ganesh D. Morphological variation in the Indian gooseberries (Phyllanthus emblica and Phyllanthus indofischeri) and the chloroplast trnL (UAA) intron as candidate gene for their identification. Plant Genet Resources 2010; 8:191-197. C. Arora D SR, Sharma S, Suttee A. Phytochemical and microscopical investigations on Emblica officinalis Gaertn. Int J Pharmac Phytoch Res 2012;4:1-4. D. Scartezzini P, Speroni E. Review on some plants of Indian traditional medicine with antioxidant activity. J Ethnopharmacol 2000; 71:23-43
  • Kirtikar KR, Basu BD, Indian Medicinal Plants, Vol-3, 1935, Page-2224
  • Suryanarayan, P., M. Saraswat, J.M. Petrash andG.B. Reddy, 2007. Emblica officinalis and its enriched tannoids delay streptozotocin-induced diabetic cataract in rats. Mol Vis., 24; 13: 1291-7.
  • Suryanarayana, P., P.A. Kumar, M. Saraswat, J.M. Petrash and G.B. Reddy, 2004. Inhibition of aldose reductase by tannoid principles of Emblica officinalis: implications for the prevention of sugar cataract. Mol Vis., 12; 10:148-54.
  • Burkill, I. H. (1966): A Dictionary of the Economic Products of the Malay Peninsula, Vol. 1, Ministry of Agriculture and Co-operatives, Kuala Lump.
  • Perianayagam, J.B., S.K. Sharma, A. Joseph and A.J. Christina, 2004. Evaluation of anti-pyretic andanalgesic activity of Emblica officinalis Gaertn. J. Ethnopharmacol., 95(1): 83-5.
  • Srikumar, R., N. J. Parthasarathy and D.R. Sheela, 2005. Immunomodulatory activity of triphala on neutrophil functions. Biol Pharm Bull., 28(8):1398-403.
  • Scartezzini, P., F. Antognoni, M.A. Raggi, F. Poli and C. Sabbioni, 2006. Vitamin C content and antioxidant activity of the fruit and of the Ayurvedic preparation of Emblica officinalis Gaertn. J Ethnopharmacol., 104(1-2): 113-8.
  • Rao, T.P., N. Sakaguchi, L.R. Juneja, E. Wada and T. Yokozawa, 2005. Amla (Emblica officinalis Gaertn.) extracts reduce oxidative stress in streptozotocin induced diabetic rats. J Med Food. 8(3): 362-8.
  • Sai, R.M., D. Neetu, P. Deepti, M. Vandana, G. Ilavazhagan, D. Kumar and W. Selvamurthy, 2003.Cytoprotective activity of Amla (Emblica officinalis) against chromium (VI) induced oxidative injury inmurine macrophages. Phytother Res., 17(4): 430-3.
  • Nosál'ová, G., J. Mokrý and K.M. Hassan, 2003. Antitussive activity of the fruit extract of Emblica officinalis Gaertn. (Euphorbiaceae).Phytomedicine., 10(6-7): 583-9.
  • Al Rehaily, A.J., T.A. Al Howiriny, M.O. Al Sohaibani and S. Rafatullah, 2002Triphala--Indian Gastroprotective effects of 'Amla' Emblica officinalis on in vivo test models in rats. Phytomedicine, R. Govindarajan and A.K. Rawat, 9(6): 515-22.
  • Veena, K., P. Shanthi and P. Sachdanandam, 2006. The biochemical alterations following administration of Kalpaamruthaa and Semecarpusanacardium in mammary carcinoma. Chem Biol Interact. 15; 161(1): 69-78.
  • Alam, M.I. and A. Gomes, 2003. Snake venom neutralization by Indian medicinal plants (Vitex A. negundo and Emblica officinalis) ischolar_main extracts. J. Ethnopharmacol., 86(1): 75-80.
  • Srikumar, R., N.J. Parthasarathy, E.M. Shankar, S. Manikandan, R. Vijayakumar, R. Thangaraj, K. Vijayananth, D.R. Sheela and U.A. Rao, 2007. Evaluation of the growth inhibitory activities of Triphala against common bacterial isolates from HIV infected patients. Phytother Res., 21(5): 476-80.
  • Saeed, S. and P. Tariq, 2007. Antibacterial activities and Coriandrum sativum against Gram negative urinary pathogens. Pak J Pharm Sci., 20(1): 32-5.
  • Kaur, S., S. Arora, K. Kaur and S. Kumar, 2002. The in vitro antimutagenic activity of Triphala--an Indian herbal drug. Food Chem Toxicol., 40(4): 527-34.
  • Srikumar, R., N.J. Parthasarathy and D.R. Sheela, 2005. Immunomodulatory activity of triphala on neutrophil functions. Biol Pharm Bull., 28(8):1398-403.
  • Sancheti, G., A. Jindal, R. Kumari and P.K. Goyal, 2005. Chemopreventive action of Emblica officinalis on skin carcinogenesis in mice. Asian Pac J Cancer Prev., 6(2): 197-201.
  • Jayaweera, D.M.A.: Medicinal Plants used in Ceylon Part 2. National Science Council of Sri Lanka. Colombo 1980.
  • Mehmood MH, Rehman A, Najeeb Ur R, Gilani AH. Studies on prokinetic, laxative and spasmodic activities of Phyllanthus emblica in experimental animals. Phytother Res 2012 ;27:10541060.
  • Gulati RK, Agarwal S, Agrawal SS. Hepatoprotective studies on Phyllanthus emblica Linn. And quercetin. Ind J ExpBiol 1995;33:261-268.
  • Lee CY, Peng WH, Cheng HY, Chen FN, Lai MT, Chiu TH. Hepatoprotective effect of Phyllanthus in Taiwan on acute liver damage induced by carbon tetrachloride. Am J Chin Med 2006;34:471-482. 59. Chatterjee A, Chattopadhyay
  • Zhang YJ, Nagao T, Tanaka T, Yang CR, Okabe H, KounoI. Antiproliferative activity of the main constituents from Phyllanthus emblica. Biol Pharm Bull 2004;27:251-255.
  • Mehmood MH, Siddiqi HS, Gilani AH. The antidiarrheal and spasmolytic activities of Phyllanthus emblica are mediated through dual blockade of muscarinic receptors and Ca2+ channels. J Ethnopharmacol 2011;133:856-865
  • Golechha M, Bhatia J, Ojha S, Arya DS. Hydroalcoholic extract of Emblica officinalis protects against kainic acid-induced status epilepticus in rats: evidence for an antioxidant, anti-inflammatory, and neuroprotective intervention. Pharm Biol 2011;49:1128-1136.
  • Sumantran VN, Kulkarni A, Chandwaskar R, Harsulkar A, Patwardhan B, Chopra A, et al. Chondroprotective potential of fruit extracts of Phyllanthus emblica in osteoarthritis. Evid Based Complement Alternat Med 2008;5:329-335.
  • Singh E SS, Pareek A, Dwivedi J, Yadav S, Sharma. Phytocheis try, traditional uses adcance rchemopreventive activity of amla (Phyllanthus emblica): The Sustainer. J Appl Pharmac Sci 2012;2:176-183.

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  • Important Uses of Amalaki (Emblica officinalis) in Indian System of Medicine with Pharmacological Evidence

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Authors

Sanjib Kumar Das
Central Ayurveda Research Institute for Hepatobiliary Disorders, Bhubaneswar, Odisha, India
Anuradha Das
Gopabandhu Ayurveda Mahavidyalaya, Puri, Odisha, India
Banamali Das
Central Ayurveda Research Institute for Hepatobiliary Disorders, Bhubaneswar, Odisha, India
Purnendu Panda
Central Ayurveda Research Institute for Hepatobiliary Disorders, Bhubaneswar, Odisha, India
G. C. Bhuyan
Central Ayurveda Research Institute for Hepatobiliary Disorders, Bhubaneswar, Odisha, India
Bipin Bihari Khuntia
Gopabandhu Ayurveda Mahavidyalaya, Puri, Odisha, India

Abstract


Emblica officinalis (syn. Phyllanthus emblica L.) is commonly known as Indian gooseberry. It has been extensively used & popularized because of its therapeutic properties having vitamin C, minerals and amino acids. The plant is used for medicinal purposes. The fruit apart from all parts of Emblica officinalis has been in nait in Ayurveda as a potent rejuvenator since days long. Various pharmaceutical properties of Emblica officinalis has been evinced previously embodying anti-oxidant, Immunomodulatory, anti-inflammatory, analgesic and antipyretic, antimicrobial, hepatoprotective, antitumor and antiulcerogenic activities either in combined formulation or Emblica officinalis proper. It is our expeditious exigencyto delve into the medicinal values of Emblica officinalis at molecular level with the succor of techniques of biotechnology though Research in medicinal plants has gained much more momentum.

Keywords


Amalaki, Gooseberry, Emblica officinalis, Pharmacological Activities, Hepatoprotective, Immunomodulatory, Antiulcerogenic.

References