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Antimicrobial Activity of Root Extracts of Cyperus rotundus (Linn) using Diarrhoea Inducing Microbes
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Due to the development of antibiotic resistance and the outbreak of infectious diseases caused by resistant pathogenic bacteria, the pharmaceutical companies and the researchers are now searching for new unconventional antibacterial agents. Hence, there is an ever-growing need to develop new antimicrobial compounds. In the present study various medicinal plants were selected to check the antimicrobial activity and Cyperus rotundus (linn) was found to have the best activity against microbes. Pet ether extract, chloroform extract and methanol extract were screened for their antimicrobial activity against various microbes which are responsible for inducing diarrhoea viz. Staphylococcus aureus, Bacillus cereus, Escherichia coli and Campylobacter jejunir using agar well diffusion method. Methanolic extract at the dose of 100 μg, have shown good antibacterial activity where as Methanolic extract at the dose of 80μg have shown moderate activity, using Loperamide as a standarad drug, against Staphylococcus aureus, Bacillus cereus, Escherichia coli and Campylobacter jejuni with zones of inhibition ranging from 19 mm to 24 mm. It might be concluded from the present study that the potential of this herb to produce useful antimicrobial compounds is great and must be better explored
Keywords
Cyperus rotundus (linn), Pet Ether, Chloroform and Methanolic Extract Loperamide Antimicrobial Activity
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- Sharma PC, Yelne MB, Dennis TJ, editors. Database on medicinal plants used in ayurveda. Vol 2.
- New Delhi: Central Council for Research in Ayurveda and Siddha; 2001. p. 481-9. http://www.wikipedia.com//Cyperus rotundus .5http:// www . google. com// plantkingdom. Com /Cyoerus rotundus. Cyperus rotundus.Usambara Invasive plants. Tropical Biology Association Retrieved2008;03:25http://www.tropicalbiology.org/research/di p/species/Cyperus%20rotundus.htm
- Rakotonirina V S, Bum EN, Rakotonirina N, Bopelet M. Sedative properties of the decoction of the rhizome of Cyperus articulatus. Fitoterapia 2001; 72:
- Cruickshank R, Duguid JP, Marmion BP, Swain RHA, editors. Medical Microbiology. Great Britain: Longman Group Ltd; 1975.
- Galvez J, Zarzuelo A, Crespo ME. Antidiarrhoeal activity of Euphorbia bitra extract and isolation of an active flavonoids constituent. Planta Med 1993. p. 333-6.
- Carrol KC, Reimer L. Infectious diarrhea: Pathogens and treatment. Leb Med J 2000; 48:2707.
- World Health Organization (WHO). The World Health Report. Geneva: WHO; 2004.
- Ganguly NK, Kaur T. Mechanism of action of cholera toxin and other toxins. Indian J Med Res 1996; 104:28 37.
- Gopal Krishna Rao, Rajasekaran S and Sanjay PN. Synthesis and antimicrobial activity of some 2-phenyl-1-{4-phenyl-1,3- thiazol-2-yl}-4-(substituted benzylidene)–imidazoline-5-ones. Indian Journal of Heterocyclic Chemistry Jan-March 2010; 19:303-304.
- Petri plates containing Int. J. Trad. Nat. Med. 2012, 1(2): 83-91
- Carrol KC, Reimer L. Infectious diarrhea: Pathogens and treatment. Leb Med J 2000; 48:270-7.
- Pazhani GP, Subramanian N, Arunchalam G, Hemalatha S, Ravichandran V. Antidiarrhoeal potential of Elephantopus scaber Linn leaf extract. Indian Drugs 2001; 38(5): 269-71
- Ezekwesili CN, Obiora KA, Ugwu OP. Evaluation of Anti- Diarrhoeal Property of Crude Aqueous Extract of Ocimum gratissimum L.(Labiatae) In Rats. Biokemistr 2004; 16(2): 122-131.
- Lagos R, Fasano A, Wasserman SS, Prado V, Martin OS, Abrego P, et al . Effect of small bowel bacterial overgrowth on the immunogenicity of single-dose live cholera vaccine CVD 103-HgR. J Inf Dis 1999;180:170
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