Research Journal of Pharmacology and Pharmacodynamics

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Antibacterial and Anti-Diarrhoel Activities of Flowers of Punica granatum Linn


Affiliations
1 Department of Pharmacognosy and Phytochemistry, K M Kundnani College of Pharmacy, Cuffe parade, Mumbai-400 005, India
2 K M Kundnani College of Pharmacy, Cuffe parade, Mumbai, India
3 Orchid Research Laboratories Ltd. Chennai, India
     

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Different extracts of Punica granatum flowers (Variety: Gulnar) were tested for antibacterial and anti-diarrhoeal activities. All the extracts showed good antibacterial activity which was comparable to that of cold water extract of Punica granatum fruit rind. Cold extracts showed better anti-diarrhoeal activity than soxhlet extracts in castor oil induced diarrhoea in rats as a model. Their anti-diarrhoeal activity was comparable to that of loperamide hydrochloride.

Keywords

Punica Granatum, Antibacterial Activity, Anti-Diarrhoeal Activity.
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  • Gislene G F, Nascimento J, Paulo C, Giuliana L. antibacterial activity of plant extracts and phytochemicals on antibiotic resistant bacteria. Brazilian Journal of Microbiology. 2000; 31:247-256.

  • Kirtikar K R and Basu B D. Indian Medicinal Plants, M/s Bishen Singh Mahendra Pal Sing, Dehra Dun and M/s Periodical Experts, Delhi, 2nd ed. Vol.II, 1975: pp.1083-1087.

  • Nadkarni A K. The Indian Materia Medica, Bombay Popular Prakashan, 3rd ed. vol.2, 1976: pp.1031-1035.

  • Balows A. manual of Clinical Microbiology, American Society for Microbiology, Washington DC, 5th ed. 1991: pp. 1105-1116.

  • Rawlins EA. Bentley's Textbook of Pharmaceutics, Bailliere Tindall, London, 8th ed.1977: pp. 515-516.

  • Hugo W B and Russell A D. Pharmaceutical Microbiology, Blackwell Scientific Publications, 5th ed.1992:pp. 274.

  • Subhash CM and Ashok Kumar C K. Studies on antidiarrhoeal activity of Ficus hispida. Leaf extract in rats. Fitoterapia. Volume 73, Issues 7-8, 2002;73(8): 663-667.

  • Seth G S. Techniques in Pharmacology, Pharmatech-96 Manual, Department of Pharmacology, Medical college and K. E. M. Hospital, Mumbai, 1996: pp.36-38.

  • Gricilda SF and Molly Thomas. Study of anti diarrhoeal activity of four medicinal plants in castor-oil induced diarrhoea. J of Ethnopharm.2001;71:73-76.

  • Shidore PP, Mujumdar SM, Shrotri DS, Mujumdar AM. Anti-Diarrheal and Anti-Inflammatory Activity of Nutmeg Myristica-Fragrans Extracts. Ind J of Pharm Sci. 1985; 47:188.

  • Pillai N R and Lillykutty L. Anti-diarrhoeal potential of Myristica fragrans seed extracts. Ancient Science of Life. 1991; XI (1 and 2): 74-77.


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  • Antibacterial and Anti-Diarrhoel Activities of Flowers of Punica granatum Linn

Abstract Views: 216  |  PDF Views: 1

Authors

Swati Patil
Department of Pharmacognosy and Phytochemistry, K M Kundnani College of Pharmacy, Cuffe parade, Mumbai-400 005, India
S. Prabhu
K M Kundnani College of Pharmacy, Cuffe parade, Mumbai, India
C. I. Jolly
K M Kundnani College of Pharmacy, Cuffe parade, Mumbai, India
S. Narayanan
Orchid Research Laboratories Ltd. Chennai, India

Abstract


Different extracts of Punica granatum flowers (Variety: Gulnar) were tested for antibacterial and anti-diarrhoeal activities. All the extracts showed good antibacterial activity which was comparable to that of cold water extract of Punica granatum fruit rind. Cold extracts showed better anti-diarrhoeal activity than soxhlet extracts in castor oil induced diarrhoea in rats as a model. Their anti-diarrhoeal activity was comparable to that of loperamide hydrochloride.

Keywords


Punica Granatum, Antibacterial Activity, Anti-Diarrhoeal Activity.

References