Research Journal of Pharmacology and Pharmacodynamics

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An Overview on Current Strategies in Breast Cancer Therapy


Affiliations
1 Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal-576104, Karnataka, India
2 Department of Pharmacognosy, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal-576104, Karnataka, India
     

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Breast cancer is the most common forms of female cancers. External factors like obesity, late pregnancies or no pregnancies, use of tobacco and alcohol have increased the risk of cancer in women. Targeted therapy is new type of cancer treatment that uses drugs precisely and attaches cancer cells with minimum damage to normal cells. It is multimodality cancer treatment regimens that include chemotherapy, surgery and radiation therapy. It has limited toxicity and target cancer cells which carry specific receptors (estrogen receptor). Third generation Aromatase Inhibitors (AIs) like Exemestane are emerging as potential therapeutic agents for breast cancer.

Keywords

Radiation Therapy, Monoclonal Antibody, Selective Estrogen Receptor Modulators (SERM), Estrogen Receptor Down Regulator (ERD), Aromatase Inhibitors (AIs).
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  • An Overview on Current Strategies in Breast Cancer Therapy

Abstract Views: 265  |  PDF Views: 0

Authors

G. K. Sudhakar
Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal-576104, Karnataka, India
Vasudev Pai
Department of Pharmacognosy, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal-576104, Karnataka, India
Arvind Pai
Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal-576104, Karnataka, India

Abstract


Breast cancer is the most common forms of female cancers. External factors like obesity, late pregnancies or no pregnancies, use of tobacco and alcohol have increased the risk of cancer in women. Targeted therapy is new type of cancer treatment that uses drugs precisely and attaches cancer cells with minimum damage to normal cells. It is multimodality cancer treatment regimens that include chemotherapy, surgery and radiation therapy. It has limited toxicity and target cancer cells which carry specific receptors (estrogen receptor). Third generation Aromatase Inhibitors (AIs) like Exemestane are emerging as potential therapeutic agents for breast cancer.

Keywords


Radiation Therapy, Monoclonal Antibody, Selective Estrogen Receptor Modulators (SERM), Estrogen Receptor Down Regulator (ERD), Aromatase Inhibitors (AIs).

References