Research Journal of Pharmacology and Pharmacodynamics

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Sleep, Health and Immunocompetence: A Review


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1 KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada-10, India
     

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Despite a century of study, we have a very little understanding of why we sleep? And it is most surprising to know that we spend nearly one third of our lives in sleep. Scientists found out another important function for sleep. It actually prepares our emotional brain for next day social and emotional interactions.

Sleep and Immune system are very much related to each other. Generally we feel sleepier when we are suffering from infection and it is believed that sleep deprivation can prone us to more infections. The sleep deprivation causes a lot of irregularities in the levels of cytokines as well as hormones. Are sleep and immune system really related? This is the point to be discussed in this review. To understand this relation a basic study on sleep and immune system components is necessary.


Keywords

NREM Sleep and REM Sleep, Immune System, IL-1β, TNF.
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  • Sleep, Health and Immunocompetence: A Review

Abstract Views: 217  |  PDF Views: 2

Authors

N. K. D. Devi
KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada-10, India
C. Srilatha
KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada-10, India
N. Vinisha
KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada-10, India
B. S. Mrudula
KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada-10, India
B. R. Madhavi
KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada-10, India

Abstract


Despite a century of study, we have a very little understanding of why we sleep? And it is most surprising to know that we spend nearly one third of our lives in sleep. Scientists found out another important function for sleep. It actually prepares our emotional brain for next day social and emotional interactions.

Sleep and Immune system are very much related to each other. Generally we feel sleepier when we are suffering from infection and it is believed that sleep deprivation can prone us to more infections. The sleep deprivation causes a lot of irregularities in the levels of cytokines as well as hormones. Are sleep and immune system really related? This is the point to be discussed in this review. To understand this relation a basic study on sleep and immune system components is necessary.


Keywords


NREM Sleep and REM Sleep, Immune System, IL-1β, TNF.

References