Research Journal of Pharmacology and Pharmacodynamics

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Role of Ficus bengalensis Leaves as a Hepatoprotective on Rifampicin Induced Hepatic Damage in Albino Rats


Affiliations
1 Hindu College Of Pharmacy, Amaravathi Road, Guntur-522002, Andhrapradesh, India
2 College of Pharmacy, Al-Jabal Al-Gharbi University, Al- Zawia, Libya
3 Centre for Pharmacy, JNT University, Hyderabad, Andhrapradesh, India
     

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The present investigation explores the hepatoprotective activity of Ficus bengalensis leaf extract in albino rats. The dried leaves of Ficus bengalensis were extracted using ethanol and tested for hepatoprotective activity on albino rats intoxicated with rifampicin (50mg/kg p.o). liver weight, pentobarbitone sleeping time, biochemical parameters was studied. Ethanolic extract of Ficus bengalensis leaf lowered the elevated levels of SGOT, SGPT and serum bilirubin indicating promising anti hepatotoxic activity.

Keywords

Ficus Bengalensis, Rifampicin, Ethanoloic Extract and Hepatoprotective.
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  • Role of Ficus bengalensis Leaves as a Hepatoprotective on Rifampicin Induced Hepatic Damage in Albino Rats

Abstract Views: 234  |  PDF Views: 2

Authors

Sumalatha Gindi
Hindu College Of Pharmacy, Amaravathi Road, Guntur-522002, Andhrapradesh, India
Nagiat T. Hawisa
College of Pharmacy, Al-Jabal Al-Gharbi University, Al- Zawia, Libya
Chandu Baburao
College of Pharmacy, Al-Jabal Al-Gharbi University, Al- Zawia, Libya
Mukkanti Khagga
Centre for Pharmacy, JNT University, Hyderabad, Andhrapradesh, India

Abstract


The present investigation explores the hepatoprotective activity of Ficus bengalensis leaf extract in albino rats. The dried leaves of Ficus bengalensis were extracted using ethanol and tested for hepatoprotective activity on albino rats intoxicated with rifampicin (50mg/kg p.o). liver weight, pentobarbitone sleeping time, biochemical parameters was studied. Ethanolic extract of Ficus bengalensis leaf lowered the elevated levels of SGOT, SGPT and serum bilirubin indicating promising anti hepatotoxic activity.

Keywords


Ficus Bengalensis, Rifampicin, Ethanoloic Extract and Hepatoprotective.

References