Research Journal of Pharmacology and Pharmacodynamics

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Healing Potential of Trichosanthes dioica Roxb on Burn Wounds


Affiliations
1 Dept. of Pharmacognosy, VNS Institute of Pharmacy, Bhopal (M.P.), India
2 Dept. of Pharmacognosy, VNS Institute of Pharmacy, Bhopal M.P., India
     

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Trichosanthes dioica Roxb is a well-known plant in the traditional medicine. Based on its traditional use, methanolic extract of the plant was selected for assessment of healing potential in the form of simple ointment using full thickness burn wound model in rats. The effect produced by the extract ointment showed significant healing when compared with the control and standard groups. All parameters such as wound contraction, epithelialization period, hydroxyproline content, and histopathological studies were observed significant (P<0.01) in comparison to control group.

Keywords

T. dioica, Burn Wound, Hydroxyproline.
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  • Healing Potential of Trichosanthes dioica Roxb on Burn Wounds

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Authors

Yogesh Shivhare
Dept. of Pharmacognosy, VNS Institute of Pharmacy, Bhopal (M.P.), India
Priya Singh
Dept. of Pharmacognosy, VNS Institute of Pharmacy, Bhopal M.P., India
U. K. Patil
Dept. of Pharmacognosy, VNS Institute of Pharmacy, Bhopal M.P., India

Abstract


Trichosanthes dioica Roxb is a well-known plant in the traditional medicine. Based on its traditional use, methanolic extract of the plant was selected for assessment of healing potential in the form of simple ointment using full thickness burn wound model in rats. The effect produced by the extract ointment showed significant healing when compared with the control and standard groups. All parameters such as wound contraction, epithelialization period, hydroxyproline content, and histopathological studies were observed significant (P<0.01) in comparison to control group.

Keywords


T. dioica, Burn Wound, Hydroxyproline.

References