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Therapeutic Uses and Pharmacological Action of Trigonella Foenum-Graecum Linn


Affiliations
1 National Institute of Ayurvedic Pharmaceutical Research, Patiala -147001, Punjab, India
2 School of Pharmaceutical Sciences, Shobhit University, Meerut, UP, India
     

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The medicinal plants are widely used by the traditional medical practitioners for curing various diseases in their day to day practice. Since ancient times, plants have been an exemplary source of medicine. Ayurveda and other Indian literature mention the use of plants in treatment of various human ailments. The leaves and seeds of Trigonella foenum-graecum Linn or fenugreek (known as Methi in Hindi), a small herb seen throughout India, have been recommended for the treatment of carminative, diuretics, small-pox, dysentery and also useful in the making of tonic. In folk medicine, Trigonella foenum-graecum has been used in the treatment of boils, cellulitis, and tuberculosis. The Trigonella foenumgraecum Linn. has also been suggested to possess Cholesterol-lowering effects, Glucose-lowering effects, Anti-inflammatory effects, Antioxidant effects and Antitumor actions.

Keywords

Medicinal Plants, Trigonella Foenum Graecum Linn., Antioxidant, Ayurveda.
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  • Atal CK, Kapoor BM. Cultivation and utilization of medicinal plants (Eds. PID CSIR), 1989.
  • Siddiqui HH. Safety of herbal drugs-an overview. Drugs News & Views 1993; 1(2): 7-10.
  • Chopra RN, Chopra IC, Handa KL, Kapoor LD. Indigenous drugs of India (Published by UN Dhar, Pvt. Ltd., Calcutta) 1993.
  • Chopra RN, Nayar SI, Chopra IC. Glossary of Indian Medicinal Plants (Published by CSIR, New Delhi) 1956.
  • Satyavati GV, Raina MK, Sharma M. Medicinal Plants of India (Published by ICMR, New Delhi), 1976.
  • Nadkararni AK, Nadkarni KM. Indian Materia Medica (Published by Popular Prakashan Pvt. Ltd.,Bombay) 1976.
  • Duke JA, Bogenschutz-Godwin MJ, deCellier J and Duke PK (2003). Trigonella foenum-graecum L. (Fabaceae) Trigonella foenum-graecum, Greek clover, Greek hay,in CRC Handbook of Medicinal Spices, CRC Press, Washington DC, p. 296.
  • Petropoulos, G.A. Fenugreek - The genus Trigonella, Taylor and Francis, London and New York. 2002.
  • Acharya S,.Srichamroen A, Basu S., Improvement in the nutraceutical properties of fenugreek (Trigonella foenumgraecum L.),2006,1-9
  • Basch, E., Ulbricht, C., Kuo, G., Szapary, P. and Smith, M. 2003. Therapeutic applications of fenugreek. Alt. Med. Rev., 8: 20-27.
  • Madar Z, Stark AH. New legume sources as therapeutic agents. Br J Nutr . 2002;88(suppl 3):S287-S292
  • Valette G, Sauvaire Y, Baccou JC, Ribes G. Hypocholesterolaemic effect of fenugreek seeds in dogs. Atherosclerosis . 1984;50:105-111.
  • Singhal PC, Gupta RK, Joshi LD. Hypocholesterolemic effect of Trigonella foenum-graecum (METHI). Curr Sci . 1982:51:136.
  • Stark A, Madar Z. The effect of an ethanol extract derived from fenugreek ( Trigonella foenum traecum ) on bile acid absorption and cholesterol levels in rats. Br J Nutr . 1993:69:277-287.
  • Sauvaire Y, Ribes G, Baccou JC, Loubatieeres-Mariani MM. Implication of steroid saponins and sapogenins in the hypocholesterolemic effect of fenugreek. Lipids . 1991;26:191-197.
  • Yadav UC, Moorthy K, Baquer NZ. Effects of sodiumorthovanadate and Trigonella foenum-graecum seeds on hepatic and renal lipogenic enzymes and lipid profile during alloxan diabetes. J Biosci . 2004;29:81-91.
  • Hannan JM, Rokeya B, Faruque O, et al. Effect of soluble dietary fiber fraction of Trigonella foenum graecum on glycemic, insulinemic, lipidemic and platelet aggregation status of Type 2 diabetic model rats. J Ethnopharmacol . 2003;88:73-77.
  • Gupta A, Gupta R, Lal B. Effect of Trigonella foenum graecum (fenugreek) seeds on glycaemic control and insulin resistance in type 2 diabetes mellitus: a double-blind placebo controlled study. J Assoc Physicians India . 2001;49:1057-1061.
  • Ribes G, Sauvaire Y, Baccou JC, et al. Effects of fenugreek seeds on endocrine pancreatic secretions in dogs. Ann Nutr Metab . 1984;28:37-43.
  • Cook, N. C., & Samman, S. (1996). Flavonoids: Chemistry, metabolism, cardioprotective effects, and dietary sources. Nutritional. Biochemistry,7, 66-76.
  • Anuradha C.V., Priyadarsini K.I., In vitro studies on antiradical and antioxidant activities of fenugreek (Trigonella foenum graecum) seeds, Food Chemistry 103 (2007) 31-37.
  • Grover J.K., Vats V., Yadav S.P., Biswas N.R., Anti-cataract activity of Pterocarpus marsupium bark and Trigonella foenum-graecum seeds extract in alloxan diabetic rats, Journal of Ethnopharmacology 93 (2004) 289-294.
  • M., Antinociceptive effects of Trigonella foenum-graecum leaves extract, Journal of Ethnopharmacology, 58 (1997) 125.
  • Raisuddin S., Sayeed I., Bin-Hafeez B., Haque R., Parvez S,Pandey S.,Immunomodulatory effects of fenugreek (Trigonella foenum graecum L.) extract in mice, International Immunopharmacology 3 (2003) 257-265.
  • Kumar, V.L., Basu, N., 1994. Anti-inflammatory activity of the latex of Calotropis procera. Journal of Ethnopharmacology 44, 123-125.
  • Vane, J.R., Botling, R.M., 1995. New insights into the mode of action of anti-inflammatory drugs. Inflammation Research 44, 1-10 .Review.9
  • Semnanian S. ,Javan M., Ahmadiani A.,. Kamalinejad, Antiinflammatory and antipyretic effects of Trigonella foenumgraecum leaves extract in the rat, Journal of Ethnopharmacology 75 (2001) 283-286.
  • Amr Amin, Aysha Alkaabi, Shamaa Al-Falasi, Sayel A. Daoud, Chemopreventive activities of Trigonella foenum graecum (Fenugreek) against breast cancer Cell Biology International, Volume 29, Issue 8, August 2005, Pages 687- 694.
  • Sur P, Das M, Gomes A, et al. Trigonella foenum graecum (fenugreek) seed extract as an antineoplastic agent. Phytother Res . 2001;15:257-259.
  • Korman SH, Cohen E, Preminger A. Pseudo-maple syrup urine disease due to maternal prenatal ingestion of fenugreek. J Paediatr Child Health . 2001;37:403-404.
  • Pandian RS, Anuradha CV, Viswanathan P. Gastroprotective effect of fenugreek seeds ( Trigonella foenum graecum ) on experimental gastric ulcer in rats. J Ethnopharmacol . 2002;81:393-397.
  • Kamal et al, Phytother Res , Fitoterapia, 1993, 7.
  • Sethi et al ,Fitoterapia,1990,61,64.
  • Sammour, R.H., El-Shanshoury, A.E.R.R., 1992. Antimicrobial activity of legume seed proteins. Botany Bulletin of Academia Sinica 33, 185-190.
  • Bhatti, M.A., M.T.J. Khan, B. Ahmad, M. Jamshaid and W. Ahmad, Fitoterapia,1996, 67, 4, 372-374.
  • Mukherjee P .K, SatheeshKumar N., _,.Bhadra S, Saha B.P. Acetylcholinesterase enzyme inhibitory potential of standardized extract of Trigonella foenum graecum L and its constituents
  • Palaniswamy M., Pradeep B. V., Sathya R. and Angayarkanni J., In vitro anti-plasmodial activity of Trigonella foenum-graecum L., oxford journal,2008

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  • Therapeutic Uses and Pharmacological Action of Trigonella Foenum-Graecum Linn

Abstract Views: 333  |  PDF Views: 2

Authors

Ajay Kr. Meena
National Institute of Ayurvedic Pharmaceutical Research, Patiala -147001, Punjab, India
Brijendra Singh
School of Pharmaceutical Sciences, Shobhit University, Meerut, UP, India
Uttam Singh
School of Pharmaceutical Sciences, Shobhit University, Meerut, UP, India
Ajay Kr. Yadav
School of Pharmaceutical Sciences, Shobhit University, Meerut, UP, India
Amit Nagariya
School of Pharmaceutical Sciences, Shobhit University, Meerut, UP, India
Kiran Sharma
School of Pharmaceutical Sciences, Shobhit University, Meerut, UP, India

Abstract


The medicinal plants are widely used by the traditional medical practitioners for curing various diseases in their day to day practice. Since ancient times, plants have been an exemplary source of medicine. Ayurveda and other Indian literature mention the use of plants in treatment of various human ailments. The leaves and seeds of Trigonella foenum-graecum Linn or fenugreek (known as Methi in Hindi), a small herb seen throughout India, have been recommended for the treatment of carminative, diuretics, small-pox, dysentery and also useful in the making of tonic. In folk medicine, Trigonella foenum-graecum has been used in the treatment of boils, cellulitis, and tuberculosis. The Trigonella foenumgraecum Linn. has also been suggested to possess Cholesterol-lowering effects, Glucose-lowering effects, Anti-inflammatory effects, Antioxidant effects and Antitumor actions.

Keywords


Medicinal Plants, Trigonella Foenum Graecum Linn., Antioxidant, Ayurveda.

References