Research Journal of Pharmacology and Pharmacodynamics

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Cytotoxic Activity of Glocihdium zeylanicum Leaf Extract


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1 Gitanjali College of Pharmacy, Cheeryal, Keesara Mandal, Rangareddy District, India
     

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In vitro cytotoxic activity of Glocihdium zeylanicum has been investigated by tryphan blue dye exclusion method at various concentrations on Ehlirich Ascites Carcinoma cells. The ethanolic extracts of Glocihdium zeylanicum has showed the significant cytotoxic property by inhibiting the dye exclusion was evaluated by comparing with standard 5-Fluorouracil. The preliminary study indicates the ethanolic extract of Glocihdium zeylanicum has significant cytotoxic property and suggests for further investigation for its antitumor and anticarcinogenic function in different models.

Keywords

Glocihdium zeylanicum, Cytotoxic Activity, EAC Cells, 5-Fluorouracil.
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  • Cytotoxic Activity of Glocihdium zeylanicum Leaf Extract

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Authors

Srivalli Tripuramallu
Gitanjali College of Pharmacy, Cheeryal, Keesara Mandal, Rangareddy District, India
Srikanth Sunkara
Gitanjali College of Pharmacy, Cheeryal, Keesara Mandal, Rangareddy District, India
Venkata Ramana Reddy Maram
Gitanjali College of Pharmacy, Cheeryal, Keesara Mandal, Rangareddy District, India

Abstract


In vitro cytotoxic activity of Glocihdium zeylanicum has been investigated by tryphan blue dye exclusion method at various concentrations on Ehlirich Ascites Carcinoma cells. The ethanolic extracts of Glocihdium zeylanicum has showed the significant cytotoxic property by inhibiting the dye exclusion was evaluated by comparing with standard 5-Fluorouracil. The preliminary study indicates the ethanolic extract of Glocihdium zeylanicum has significant cytotoxic property and suggests for further investigation for its antitumor and anticarcinogenic function in different models.

Keywords


Glocihdium zeylanicum, Cytotoxic Activity, EAC Cells, 5-Fluorouracil.

References