Research Journal of Pharmacology and Pharmacodynamics

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Evaluation of Anti-Inflammatory Activity of Leaf Extract of Morinda Citrifolia L. (Noni)


Affiliations
1 Department of Pharmacology, K.L.R. Pharmacy College, Contractors Colony, Paloncha, A.P., India
2 Department of Pharmaceutics, Institute of Pharmacy and Technology, Salipur, Orissa, India
3 College of Pharmaceutical Sciences, Puri, Orissa, India
     

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Morinda citrifolia L. (Noni) (Rubiaceae) has been used in folk remedies by Polynesians, Indians for over 2000 years, and is reported to have a broad range of therapeutic effects, including antibacterial, antiviral, antifungal, antitumor, analgesic, hypotensive, and immune enhancing effects. Petroleum ether extract of leaves of Morinda citrifolia L. (Noni) was studied for its in-vivo anti-inflammatory potential using carageenen induced rat paw edema and cotton pellet induced granuloma methods. The results of the study indicate that the petroleum ether extract possess significant anti-inflammatory activity at doses 150mg/kg and 300mg/kg.

Keywords

Immune Enhancing, Antiviral, Antifungal, Antitumor, Granuloma.
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  • Evaluation of Anti-Inflammatory Activity of Leaf Extract of Morinda Citrifolia L. (Noni)

Abstract Views: 229  |  PDF Views: 2

Authors

Khuntia Tapas Kumar
Department of Pharmacology, K.L.R. Pharmacy College, Contractors Colony, Paloncha, A.P., India
D. S. Panda
Department of Pharmaceutics, Institute of Pharmacy and Technology, Salipur, Orissa, India
S. Khuntia
College of Pharmaceutical Sciences, Puri, Orissa, India

Abstract


Morinda citrifolia L. (Noni) (Rubiaceae) has been used in folk remedies by Polynesians, Indians for over 2000 years, and is reported to have a broad range of therapeutic effects, including antibacterial, antiviral, antifungal, antitumor, analgesic, hypotensive, and immune enhancing effects. Petroleum ether extract of leaves of Morinda citrifolia L. (Noni) was studied for its in-vivo anti-inflammatory potential using carageenen induced rat paw edema and cotton pellet induced granuloma methods. The results of the study indicate that the petroleum ether extract possess significant anti-inflammatory activity at doses 150mg/kg and 300mg/kg.

Keywords


Immune Enhancing, Antiviral, Antifungal, Antitumor, Granuloma.

References