Research Journal of Pharmacology and Pharmacodynamics

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Screening of Anti-Inflammatory Potential of Berberis coriaceae Leaves by HRBC Membrane Stabilization


Affiliations
1 Columbia Institute of Pharmacy, Tekari, Raipur (C.G.), India
2 Oriental College of Pharmacy, Patel Nagar, Bhopal (M.P.), India
     

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The present study was undertaken to screen anti-inflammatory activity of alcohol and aqueous extracts of leaves from Berberis coriaceae against HRBC membrane stabilization. The prevention of hypotonicity induced HRBC membrane lysis was taken as a measure of the anti-inflammatory activity. Both the extracts showed a biphasic effect on the membrane stabilization. Their activities are comparable to that of the standard drug diclofenac sodium. However their activities decreased with time.

Keywords

Berberis coriaceae, HRBC, Diclofenac Sodium.
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  • Screening of Anti-Inflammatory Potential of Berberis coriaceae Leaves by HRBC Membrane Stabilization

Abstract Views: 296  |  PDF Views: 0

Authors

Amit Roy
Columbia Institute of Pharmacy, Tekari, Raipur (C.G.), India
Ram Kumar Sahu
Oriental College of Pharmacy, Patel Nagar, Bhopal (M.P.), India

Abstract


The present study was undertaken to screen anti-inflammatory activity of alcohol and aqueous extracts of leaves from Berberis coriaceae against HRBC membrane stabilization. The prevention of hypotonicity induced HRBC membrane lysis was taken as a measure of the anti-inflammatory activity. Both the extracts showed a biphasic effect on the membrane stabilization. Their activities are comparable to that of the standard drug diclofenac sodium. However their activities decreased with time.

Keywords


Berberis coriaceae, HRBC, Diclofenac Sodium.

References