Research Journal of Pharmacology and Pharmacodynamics

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Screening of Anti-Inflammatory Potential of Berberis coriaceae Leaves by HRBC Membrane Stabilization


Affiliations
1 Columbia Institute of Pharmacy, Tekari, Raipur (C.G.), India
2 Oriental College of Pharmacy, Patel Nagar, Bhopal (M.P.), India
     

   Subscribe/Renew Journal


The present study was undertaken to screen anti-inflammatory activity of alcohol and aqueous extracts of leaves from Berberis coriaceae against HRBC membrane stabilization. The prevention of hypotonicity induced HRBC membrane lysis was taken as a measure of the anti-inflammatory activity. Both the extracts showed a biphasic effect on the membrane stabilization. Their activities are comparable to that of the standard drug diclofenac sodium. However their activities decreased with time.

Keywords

Berberis coriaceae, HRBC, Diclofenac Sodium.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Basbaum AI and Field HL. Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry. Ann. Rev. Neurosci. 1984; 7: 309-338.

  • Ebrahimzadeh MA, Mahmoudi M and Salimi E. Antiinflammatory activity of Sambucus ebulus hexane extracts. Fitoterapia, 2006; 77: 146-48.

  • Winter CA, Porter CC. Effect of alteration in side chain upon antiinflammatory and liver glycogen activities in hydrocortisone ester. J Amer Pharmacol Soci 1957;46:515-9.

  • Chopra RN. Indigenous Drug of India, IInd edition. Published by Academic Publisher. Calcutta. 2006. pg 290.

  • Gandhidasan R., Thamaraichelvan A. and Baburaj S., Antiinflammatory action of Lannea coromandelica By HRBC membrane stabilization, Fitoterapia, LXII, 1, 1991;81-83.

  • Suleyman H, Demirezer LO, Kuruuzum A, Banoglu ZN, Gocer F, Ozbakir G, et al. Antiinflammatory effect of the aqueous extract from Rumex patientia L ischolar_mains. J Ethnopharmacol 1991;65:141-8.

  • Sankari G, Mounnissamy VM, and Balu V, Evaluation of antiinflammatory and membrane stabilizing properties of ethanolic extracts of Diptheracanthus prostatus(Acanthaceae), Amala Research Bulletin, 2009: 29; 188-89.


Abstract Views: 218

PDF Views: 0




  • Screening of Anti-Inflammatory Potential of Berberis coriaceae Leaves by HRBC Membrane Stabilization

Abstract Views: 218  |  PDF Views: 0

Authors

Amit Roy
Columbia Institute of Pharmacy, Tekari, Raipur (C.G.), India
Ram Kumar Sahu
Oriental College of Pharmacy, Patel Nagar, Bhopal (M.P.), India

Abstract


The present study was undertaken to screen anti-inflammatory activity of alcohol and aqueous extracts of leaves from Berberis coriaceae against HRBC membrane stabilization. The prevention of hypotonicity induced HRBC membrane lysis was taken as a measure of the anti-inflammatory activity. Both the extracts showed a biphasic effect on the membrane stabilization. Their activities are comparable to that of the standard drug diclofenac sodium. However their activities decreased with time.

Keywords


Berberis coriaceae, HRBC, Diclofenac Sodium.

References