Research Journal of Pharmacology and Pharmacodynamics

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Anti Gastric Ulcer Studies on Certain Siddha Drugs


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1 Department of Pharmacology RVS College of Pharmaceutical Sciences, Sulur, Coimbatore-641402, India
     

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The Traditional system of medicines like the Ayurveda, Unani and Siddha have provided the mankind with useful drug and are of mostly of natural origin and hence are believed to possess less side effects. Research for new anti gastric ulcer drugs in the traditional system of medicine made us survey the literature in the Siddha system of medicines for possible leads and suggestions. The literature provided with us the following drugs. Nilvarai chroonam, Bilwadi lehyam, Triphala choornam and Thamarai parpam. The Siddha drug were studied for anti gastric activity using different animal models like pylorus ligation and drug induced ulcer in rats and biochemical studies like SGOT,SGPT and alkaline phosphatase. The results obtained revealed that all the drugs investigated for their anti gastric ulcer activity had significant antiulcer action evidenced by the low ulcer scoring as well as low free acidity content. These results validate the therapeutic claims made of these drugs in the literature as anti ulcer drugs as well as the siddha clinicians.

Keywords

Ayurveda, Unani, Siddha, Nilvarai Chroonam, Bilwadi Lehyam, Triphala Choornam, Thamarai Parpam.
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  • Anti Gastric Ulcer Studies on Certain Siddha Drugs

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Authors

D. Benito Johnson
Department of Pharmacology RVS College of Pharmaceutical Sciences, Sulur, Coimbatore-641402, India
Appalaraju Gorle
Department of Pharmacology RVS College of Pharmaceutical Sciences, Sulur, Coimbatore-641402, India
Sai Kishore Paleti
Department of Pharmacology RVS College of Pharmaceutical Sciences, Sulur, Coimbatore-641402, India
Ashok Javvadi
Department of Pharmacology RVS College of Pharmaceutical Sciences, Sulur, Coimbatore-641402, India

Abstract


The Traditional system of medicines like the Ayurveda, Unani and Siddha have provided the mankind with useful drug and are of mostly of natural origin and hence are believed to possess less side effects. Research for new anti gastric ulcer drugs in the traditional system of medicine made us survey the literature in the Siddha system of medicines for possible leads and suggestions. The literature provided with us the following drugs. Nilvarai chroonam, Bilwadi lehyam, Triphala choornam and Thamarai parpam. The Siddha drug were studied for anti gastric activity using different animal models like pylorus ligation and drug induced ulcer in rats and biochemical studies like SGOT,SGPT and alkaline phosphatase. The results obtained revealed that all the drugs investigated for their anti gastric ulcer activity had significant antiulcer action evidenced by the low ulcer scoring as well as low free acidity content. These results validate the therapeutic claims made of these drugs in the literature as anti ulcer drugs as well as the siddha clinicians.

Keywords


Ayurveda, Unani, Siddha, Nilvarai Chroonam, Bilwadi Lehyam, Triphala Choornam, Thamarai Parpam.

References