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Evaluation of Erythrocyte Disorders with Mean Corpuscular Volume (MCV) and Red Cell Distribution Width (RDW)
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The Red Cell Distribution width (RDW) which provides a Quantitative measure of heterogeneity of red cells in the peripheral Blood and the mean Corpuscular Volume (MCV) are part of the routine red cell indices reported by automated blood analysis. The study evaluated 250 cases with a wide range of erythrocyte disorders and determined the diagnostic utility of the Red Cell Distribution width (RDW) in relation to the Mean Corpuscular Volume (MCV). Six different groups of erythrocyte disorders by Mean Corpuscular Volume (MCV) and Red Cell Distribution Width (RDW) values are described: Low Mean Corpuscular Volume (MCV)/normal red cell distribution width (RDW), Low Mean Corpuscular Volume (MCV) /High Red Cell distribution width (RDW), normal Mean Corpuscular Volume (MCV)/Normal Red Cell Distribution width (RDW), Normal Mean Corpuscular Volume (MCV)/high Red Cell Distribution width (RDW). High Mean Corpuscular Volume/normal Red Cell Distribution width, High Mean Corpuscular Volume/High Red Cell Distribution width.
This combination established a use full differential diagnosis of erythrocyte disorders. The data provides a base line against which future studies of infants and children can be compared, though each Laboratory has to verify its own norms, it should be cautioned that different electronic counters yield different. Red Cell Distribution width (RDW) values, so there have to be when reporting reference values. The Red Cell Distribution width (RDW) may find its best use as a guide in the differential diagnosis of anemia rather than as a definitive test per se. In 1957 a study group of World Health Organization (W.H.O.) has expressed the view that in order to get a comprehensive picture of disease or health problem more and more studies have to be carried out, Garg Narendra K.(1). This prompted the authors to undertake this study.
Keywords
Mean Corpuscular Volume, Red Cell Distribution Width, Iron Deficiency Anemia.
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