Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Antimicrobial Potential of Ethanolic Extract of Psidium guajava Leaf and its Isolated Fraction Against Some Pathogenic Microorganisms


Affiliations
1 P.G. Department of Biotechnology, Sree Narayana Guru College, Coimbatore, Tamil Nadu, India
2 P.G. and Research Department of Zoology, Government Arts College, Tamil Nadu, India
     

   Subscribe/Renew Journal


The present investigation focuses on the antimicrobial potential of leaf extract of Psidium guajava and its isolated fraction against the selected bacterial strains. Ethnolic leaf extract of Psidium guajava and its isolated fraction was more potent in inhibiting the growth of pathogenic Escherichia coli, Staphylococcus aureus and Staphylococcus epidermidis with different degree of inhibition. The antibacterial activity was more effect in isolated fraction compound than the plant extract. The results support the notion that plant extract containing compound may have many roles in pharmaceuticals as antimicrobial formulations.

Keywords

Psidium guajava, Escherichia Coli, Staphylococcus Aureus, Staphylococcus Epidermidis.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Abdallah EM. Plants: An alternative source for antimicrobials. Journal of Applied Pharmaceutical Science, 2011; 01(06): 16-20.
  • World Health Organization WHO. Traditional medicine strategy 2002; 2002-2005.
  • Nwinyi OC, Chinedu NS and Ajani OO. Evaluation of antibacterial activity of Psidium guajava and Gongronema Latifolium. J. Med. Plants Res. 2008; 2(8): 189-192.
  • Iwu MM. Handbook of African Medicinal Plants. CRC Press, ISBNNo.0-8493-4266-X. pp. 1993; 786-789.
  • Caceres A, Fletes L, Aguilar L, Ramirez O, Figueroa L, Taracena AM and Samoya B. Plants used in Guatemala for the treatment of gastrointestinal disorgers. III. Confirmation of activity against enterobacterial of 19 plants extract. J. Ethnopharmacol, 1993; 38: 31-38.
  • Jaiarj P, Khoohaswan P, Wongkrajang Y, Peungvicha P, Suriyawong P, Saraya ML and Ruangsomboon O. Anticough and antimicrobial activities of Psidium guajava Linn. leaf extract. J. Ethnopharmacol, 1999; 67: 203-212.
  • Gnan SO and Demello MT. Inhibition of Staphylococcus aureus by aqueous Goiaba extracts. J. Ethnopharmacol, 1999; 68: 103- 108.
  • Coutino-Rodriguez R, Hernandez-Cruz P and Giles-Rios H. Lectins in fruits having gastrointestinal activity: their participation in the heamagglutinating roperty of Escherichia coli O157:H7. Archive Med. Res, 2001; 32: 251-257.
  • Vieira RHS, dos F, Rodrigues D, dos P, Goncalves FA, Menezes FGR, de Aragao JS and Sousa OV. Microbicidal effect of medicinal plant extracts (Psidium guajava Linn. and Carica papaya Linn.) upon bacteria isolated from fish muscle and known to induce diarrhea in children. Instituto de Ciencias do Mar-UFC, Ceara, Brazil. Revista do Instituto de Medicina Tropical de Sao Paulo. 2001; 43 (3): p.145-148.
  • Abdelrahim SI, Almagboul AZ, Omer ME and Elegami A. Antimicrobial activity of Psidium guajava L. Fitoterapia, 2002; 73: 713-5.
  • Qadan F, Thewaini AJ, Al DA, Afifi R, Elkhawad A and Matalka KZ. The antimicrobial activities of Psidium guajava and Junglans regia leaf extracts to acne-developing organisms. Am. Chin. Med. 2005; 33: 197-204.
  • Tiwar S and Singh A. Toxic and sub-lethal effects of oleadrin on biochemical parameters of freshwater air breathing murrel, Chant punctatus (Bloch.). Indian J. Exp. Biolo. 2004; 42: 413- 418.
  • Lewis K and Ausubel FM. Prospects of plant derived antibacterials. Nat. Biotechnol. 2006; 24: 1504-1507.
  • Fransworth NR, Akerele O, Bingel AS, Soejarto DD and Guo ZG. Medicinal plants in therapy. Bulletin of the World Health Organization, 1985; 63: 965-981.
  • Akanji MA, Adeyemi OS, Oguntoye SO and Sulyman F. Psidium guajava extract reduces trypanosomosis associated lipid peroxidation and raises glutathione concentrations in infected animals. EXCLI J, 2009; 8: 148-154.
  • Hernandez, Dolores F. Plants of the Philippines. M&L Licudine Enterprises. First Printing 1971. 2nd. edition 1980. Printed in the Philippines. University of the Philippines: Chairman: Consuelo V. Asis. D, No ISBN number. 1980;
  • Limsong J, Benjavongkulchai E and Kuvatanasuchati J. Inhibitory effects of some herbal extracts on adherence of Streptococcus mutans. J. Ethnopharmacol, 2004; 92: 281-289.
  • Brotz-Oesterhelt H, Beyer D, Kroll HP, Endermann HPR and Ladel C. Dysregulation of bacterial proteolytric machinery by a new class of antibiotics. Nat. Med, 2005; 11: 1082-1087.
  • Morton JF. Atlas of Medicinal Plants of Middle America: Bahamas to Yucatan. Springfield Charles Thomas, Illinois, USA. 1981;

Abstract Views: 254

PDF Views: 3




  • Antimicrobial Potential of Ethanolic Extract of Psidium guajava Leaf and its Isolated Fraction Against Some Pathogenic Microorganisms

Abstract Views: 254  |  PDF Views: 3

Authors

M. Shakeera Banu
P.G. Department of Biotechnology, Sree Narayana Guru College, Coimbatore, Tamil Nadu, India
K. Sujatha
P.G. and Research Department of Zoology, Government Arts College, Tamil Nadu, India

Abstract


The present investigation focuses on the antimicrobial potential of leaf extract of Psidium guajava and its isolated fraction against the selected bacterial strains. Ethnolic leaf extract of Psidium guajava and its isolated fraction was more potent in inhibiting the growth of pathogenic Escherichia coli, Staphylococcus aureus and Staphylococcus epidermidis with different degree of inhibition. The antibacterial activity was more effect in isolated fraction compound than the plant extract. The results support the notion that plant extract containing compound may have many roles in pharmaceuticals as antimicrobial formulations.

Keywords


Psidium guajava, Escherichia Coli, Staphylococcus Aureus, Staphylococcus Epidermidis.

References