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A Life Threatening Disease Leptospirosis
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Leptospirosis is a widespread infectious disease that is prevalent in tropical regions due to the favorable environmental survival conditions. The various species of leptospira of the spirochete family are responsible for transmission of disease. Leptospirosis is a biphasic disease that begins flu like symptoms. The first phase resolves and the patient is briefly asymptomatic until the second phase begins. Leptospirosis starts suddenly, with a severe headache, redness in the eyes, muscle pains, fatigue and nausea and a fever of 39°C or above. The diagnosis of Leptospirosis in generally carried out by direct visualization of leptospirosis in blood or urine by darkfield microscopic examination. And various staining methods are also used for the diagnosis. The antibiotic therapy is generally used for the treatment purpose.
Keywords
Leptospirosis, Transmission, Diagnosis, Treatment.
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- Yasuda PH, Steigerwalt AG, Sulzer KR, et al. Deoxyribonucleic acid relatedness between serogroups and serovars in the family Leptospiraceae with proposals for seven new Leptospiraspecies. Int J Syst Bacteriol. 1987;37:407-415.
- Brenner DJ, Kaufmann AF, Sulzer KR, et al. Further determination of DNA relatedness between serogroups and serovars in the family Leptospiraceae with a proposal for Leptospira alexanderi sp. nov. and four new Leptospira genomospecies. Int J Syst Bacteriol.1999;49:839-858.
- Stimson AM. Note on an organism found in yellow-fever tissue. Publ Health Rep. 1907;22:541.
- Edward Rhodes Stitt; Richard Pearson Strong (1944). Stitt's Diagnosis, prevention and treatment of tropical diseases (7th ed.). York, PA: Blakiston.
- Everard JD. Leptospirosis. In: Cox FEG, ed. The Wellcome Trust Illustrated History of Tropical Diseases. London:The Wellcome Trust; 1996:111-119, 416-418.
- (Ward MP, Glickman LT, Guptill LF. Prevalence of and risk factors for leptospirosis among dogs in the United States and Canada: 677 cases (1970-1998). J Am Vet Med Assoc. 2002;220:53-58.)
- Brown PD, Gravekamp C, Carrington DG, et al. Evaluation of the polymerase chain reaction for early diagnosis of leptospirosis.J Med Microbiol. 1995;43:110-114.
- Merien F, Baranton G, Perolat P. Comparison of polymerase chain reaction with microagglutination test and culture for diagnosis of leptospirosis. J Infect Dis. 1995;172:281-285.
- Slack A, Symonds M, Dohnt M, et al. Evaluation of a modified Taqman assay detecting pathogenic Leptospira spp. Against culture and Leptospira-specific IgM enzyme-linked immunosorbent assay in a clinical environment. Diag Microbiol Infect Dis. 2007;57:361-366.)
- Alves VAF, Vianna MR, Yasuda PH, et al. Detection of leptospiral antigen in the human liver and kidney using an immunoperoxidase staining procedure. J Pathol. 1987;151:125-131.
- Guarner J, Shieh W-J, Morgan J, et al. Leptospirosis mimicking acute cholecystitis among athletes participating in a triathlon. Hum Pathol. 2001;32:750-752.)
- Lomar AV, Diament D, Torres JR. Leptospirosis in Latin America. Infect Dis Clin N Am 2000;14:23-39.
- Alves VAF, Gayotto LCC, Yasuda PH. Leptospiral antigen in the kidney of experimentally infected guinea pigs and their relation to the pathogenesis of renal injury. Exp Pathol 1991;42:81-93.
- Eficacia y seguridad de una vacuna contra la leptospirosis humana en Cuba.] Rev Panam Salud Publica. 2004;15:249-255.
- Guidugli F, Castro AA, Atallah NA. Antibiotics for preventing leptospirosis (Cochrane Review). In:The Cochrane Library. Issue 3. Oxford: Update Software;2001.
- Lomar AV, Diament D, Torres JR. Leptospirosis in Latin America. Infect Dis Clin N Am 2000;14:23-39.
- Farr RW. Leptospirosis. Clin Infect Dis 1995;21:1-8.
- Feigin RD, Anderson DC. Human leptospirosis. Crit Rev ClinLab Sci 1975;5:413-65.
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