Open Access
Subscription Access
Open Access
Subscription Access
Phytochemical Investigation and Antidiabetic Activity Studies of Moringa oliefera Roots
Subscribe/Renew Journal
Moringa oliefera Lam. is one of the best known and most widely distributed and naturalized species of a monogenetic family Moringaceae. The ischolar_mains of plant were extracted with ethanol by soxhlet technique and aqueous extract of ischolar_mains are prepared by maceration technique. Both the extracts are subjected to phytochemical screening. Require quantity of alcoholic and aqueous extracts were obtained from the plant which is used as test drug in Streptozotocin induced diabetic model. The present investigation is undertaken to study the effect of the potential hypoglycemic effect of Moringa oliefera Lam. in Streptozotocin (STZ) induced Diabetes Mellitus.
Keywords
Antidiabetic activity, Moringa oliefera, Streptozotocin, Glipizide.
Subscription
Login to verify subscription
User
Font Size
Information
- Kirtikar KR and Basu BD. Indian Medicinal Plants. (M/s Bishen Singh, Mahendra Pal Singh, New Cannaught Place, Dehra Dun), 2nd Edn, Reprint, 1975, 35(1), pp. 676-683.
- Fuglie LJ. New Uses of Moringa Studied in Nicaragua. ECHO Development Notes #68, June, 2000.
- Fahey JW, AT Zalcmann, and P Talalay. The chemical diversity and distribution of glucosinolates and isothiocyanates among plants. Phytochemistry, 2000; 56(1): 5-51.
- Kalkunte S, Swamy N, Dizon DS, Brard L. Benzyl isothiocyanate (BITC) induces apoptosis in ovarian cancer cells in vitro. J Exp Ther Oncol., 2006; 5: 287-300.
- Satyan KS, Swamy N, Dizon DS, Singh R, Granai CO, Brard L. Phenethyl isothiocyanate (PEITC) inhibits growth of ovarian cancer cells by inducing apoptosis: role of caspase and MAPK activation. Gynecol Oncol., 2006; 103:261-270.
- Dahot MU. Antimicrobial activity of small protein of Moringa oliefera leaves. Journal of Islamic Academy of Sciences 1998; 11(1): 27-32.
- Gupta M. Mazumder UK, Chakrabarti S. CNS activities of methanolic extract of Moringa oliefera ischolar_main in mice. Fitoterapia., 1999; 70: 244-250.
- Guevara AP, Vargas C, Sakurai H, Fujiwara Y, Hashimoto K, Maoka T, et al. An anti-tumor promoter from Moringa oliefera Lam. Mutation Res., 1999; 440(2): 181-188.
- Lalas S and Tsaknis J. Extraction and identification of natural antioxidant from the seeds of the Moringa oliefera tree variety of Malawi J Am Oil Chemists Soc., 2002; 79(7): 677-683.
- Ray K, Hazra R and Guha D. Central inhibitory effect of Moringa oliefera ischolar_main. extract, Possible role of neurotransmitters, Indian J Exp Biol., 2003; 41(11): 1279-1284.
- Ruckmani K, Kacimani S, Anandan R and Jayker B. Effect of Moringa oliefera Lam. on Paracetamol - induced hepatotoxicity, Indian J Pharm Sci., 1998; 60(1): 33-35.
- The Wealth of India- A Dictionary of raw materials, Publications and information Directorate,CSIR, New Delhi, 1956, pp. 35-36.
- Harbone JB. Phytochemical Method, Chapman Hall, 1988; pp. 117-119.
- Mohammed A. Text Book of Pharmacognosy, CBS Publishers and Distributors, 1994; pp. 81- 447.
- Agrawal OP. Advanced practical organic chemistry, Goel Publishing House, 2000; pp. 43-59.
- Divakar MC. Plant Drug Evaluation, CD Remedies Publication, 2003; pp. 49-89.
- S. Kumar, V. Kumar, Prakash O. Antidiabetic and hypolipidemic activities Of Hibiscus Tiliaceus (L.) flowers extract in Streptozotocin induced diabetic rats. Pharmacologyonline, 2010; 2: 1037-1044.
- Chatterji S, Singh RK, Shukla S, Yadav DK, Watal G. Glycemic effect of freeze dried Murraya koenigii - evidence based study. International Journal Of Pharma And Bio Sciences, 2010; 1(2): 1-9.
- Teckman, JH, Loethen JK, Perlmutter DH. Fasting in a1-antitrypsin deficient liver: constitutive activation of autophagy. Am. J. Physiol., 2002; 263: G1156-G1165.
- Thorup C, Ollerstam A, Persson EG, Torffvit O. Increased tubule glomerular feedback reactivity is associated with increased NO production in the Streptozotocin-diabetic rat. J. Diabetes Compl., 2000; 14: 46-52.
Abstract Views: 227
PDF Views: 2